1-deoxynojirimycin hmoov

Shaanxi Yuantai Biological Technology Co., Ltd. yog ib qho ntawm feem txhim khu kev qha manufacturers thiab lwm tus neeg ntawm 1-deoxynojirimycin nyob rau hauv Suav teb. Nrog kev paub ntau, peb zoo siab tos txais koj rau cov lag luam wholesale bulk 1-deoxynojirimycin rau muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.

1-Deoxynojirimycin, DNJ luv luv, yog ib qho alkaloid muab rho tawm los ntawm mulberry nplooj thiab hauv paus bark, thiab kuj muaj nyob rau hauv lwm yam nroj tsuag thiab microorganisms. Cov khoom no yog ib qho muaj zog -glucosidase inhibitor, uas tuaj yeem cuam tshuam kev hloov pauv cov suab thaj hauv tib neeg lub cev thiab txo cov suab thaj hauv cov ntshav. Tom qab nkag mus rau hauv tib neeg lub cev, nws tuaj yeem cuam tshuam cov hmoov txhuv nplej siab thiab qab zib los ntawm sucrase, maltase, -glucosidase, thiab -amylase hauv tib neeg lub cev, yog li thaiv kev nqus cov piam thaj los ntawm tib neeg lub cev, inhibiting qhov nce hauv cov ntshav qab zib, thiab ua tiav cov txiaj ntsig ntawm kev tiv thaiv thiab kho ntshav qab zib, kev noj zaub mov tsis zoo. Tsis tas li ntawd, DNJ tuaj yeem cuam tshuam tus kab mob ua haujlwm rau qee yam.

Cov nyhuv hypoglycemic ntawm DNJ

DNJ yog ib qho zoo inhibitor ntawm -glucosidase nyob rau hauv tag nrho cov tsiaj, uas yuav txo tau postprandial hyperglycemia los ntawm kev txo cov carbohydrate digestion thiab qabzib nqus. Vim yog cov cuab yeej no, DNJ tuaj yeem siv los txo cov ntshav qab zib thiab nws cov teeb meem, rog rog thiab lwm yam teeb meem.

Hypoglycemic Mechanism

Triple pathway, feem ntau hypoglycemic

Raws li lub zog inhibitor ntawm cov piam thaj metabolism hauv cov enzymes (xws li -glucosidase, hexokinase, glucuronidase thiab glycogen phosphatase, thiab lwm yam), DNJ tuaj yeem cuam tshuam cov txheej txheem degradation ntawm polysaccharides thiab txo cov ntshav qab zib tom qab noj mov, ruaj khov ceev ceev ntshav qab zib. Tsis tas li ntawd, DNJ tseem muaj cov txiaj ntsig ntawm kev nce insulin rhiab heev thiab txhim kho insulin tsis kam.

Txo cov ntshav qab zib tom qab noj mov

-glucosidase feem ntau yog muab faib rau hauv tib neeg txoj hnyuv thiab ua lub luag haujlwm tseem ceeb hauv kev decomposition ntawm carbohydrates. Lawv yog lub luag haujlwm rau kev rhuav tshem oligosaccharides xws li oligosaccharides hauv cov khoom noj rau hauv cov suab thaj yooj yim xws li qabzib. Cov piam thaj no nkag mus rau hauv lub cev los ntawm cov phab ntsa hauv plab hnyuv, ua rau muaj kev nce ntxiv hauv cov ntshav qab zib concentration hauv tib neeg lub cev. DNJ yog lub ntuj thiab muaj zog -glucosidase inhibitor, uas tuaj yeem sib tw khi -glucosidase hauv txoj hnyuv me, thiab nws txoj kev sib raug zoo muaj zog dua li ntawm oligosaccharides xws li sucrose thiab maltose thiab -glucosidase, txo oligosaccharides.} thiab Qhov tshwm sim ntawm -glucosidase khi, yog li inhibiting decomposition ntawm fructose rau hauv qabzib, ntau cov suab thaj yuav tsis nqus thiab xa mus rau txoj hnyuv loj. Vim tias qhov kev txiav txim ntawm DNJ, cov piam thaj tsawg dua nkag mus rau hauv cov ntshav, yog li cov ntshav qab zib tuaj yeem tswj hwm tau zoo.

Stabilize yoo ntshav qab zib

DNJ muaj cov haujlwm inhibitory ntawm glycogen phosphorylase, uas tuaj yeem ua rau cov txheej txheem ntawm daim siab glycogen degradation mus rau hauv qabzib, yog li txhim kho cov ntshav qab zib sai. "Ntau" cov piam thaj hauv lub cev yog khaws cia hauv daim siab hauv daim ntawv ntawm glycogen. Glycogen tuaj yeem decomposed rau hauv qabzib nyob rau hauv kev ua ntawm glycogen phosphorylase, thiab tso tawm mus rau hauv cov ntshav los muab cov kev xav tau ntawm cov leeg thiab lwm yam hauv nruab nrog cev. Glycogen yog ib qho ntawm lub zog tseem ceeb rau kev ua si lub cev. Nrog rau kev sib hloov pauv ntawm glycogen thiab qabzib, cov ntshav qab zib ntawm cov neeg ib txwm nyob hauv qhov sib npaug dynamic. Hauv cov neeg mob ntshav qab zib mellitus, vim muaj kev cuam tshuam ntawm cov metabolism hauv qabzib, glycogen ntau dhau yuav decomposed rau hauv qabzib, ua rau muaj qhov txawv txav ntawm cov ntshav qabzib ceev. DNJ tuaj yeem cuam tshuam kev ua haujlwm ntawm glycogen phosphorylase thiab tiv thaiv kev nce qib ntawm cov piam thaj hauv cov ntshav los ntawm decomposition ntawm ntau dhau glycogen rau hauv cov piam thaj, thiaj li ua tiav cov txiaj ntsig ntawm stabilizing ntshav qab zib.

Txhim kho insulin tsis kam

DNJ tuaj yeem txhim kho cov tsos mob ntawm insulin tsis kam los ntawm kev kho cov lipid metabolism, txo qis cov piam thaj thiab kev nkag siab ntawm insulin. Insulin tsis kam yog hais txog ntau yam laj thawj (tsuas yog suav nrog cov caj ces thiab kev rog), uas ua rau insulin txhawb nqa cov piam thaj thiab siv cov txiaj ntsig, thiab lub cev them nyiaj rau kev tso tawm ntau dhau ntawm insulin. Insulin tsis kam ua rau hyperinsulinemia txhawm rau tswj kev ruaj ntseg ntawm cov ntshav qab zib hauv lub cev. Yog hais tias tib neeg lub cev nyob rau hauv lub xeev ntawm insulin tsis kam mus ntev, nws yuav ua rau kom lub nra ntawm lub txiav, uas yuav ua rau lub txiav tsis ua hauj lwm ntawm cov tshuaj insulin, thiab tej zaum yuav ua rau mob ntshav qab zib. DNJ tuaj yeem txhim kho cov tsos mob ntawm insulin tsis kam los ntawm kev tswj cov ntshav qab zib kom noj qab haus huv, kho cov metabolism hauv lipid, thiab ua kom cov insulin rhiab heev.

Daim ntawv thov kev taw qhia

Nws yog dav siv hauv kev lag luam khoom noj qab haus huv vim nws cov txiaj ntsig ntawm kev txo cov ntshav qab zib.

Kev tshawb fawb siv adenine-induced mob raum kab mob nas qauv ntsuas qhov cuam tshuam ntawm mulberry twig alkaloids ntawm lub raum ua haujlwm thiab lub raum pathological qauv. Cov kws tshawb fawb tau ntsuas qhov ntsuas lub raum ua haujlwm xws li ntshav creatinine thiab ntshav urea nitrogen, thiab pom qhov ntsuas ntawm lub raum kev puas tsuaj thiab interstitial fibrosis. Ib txhij, ua ke nrog transcriptomics thiab proteomics tsom xam, lawv tau soj ntsuam cov kev hloov pauv ntawm cov molecular hauv lub raum cov ntaub so ntswg, tsom mus rau fatty acid oxidation, mitochondrial muaj nuj nqi, thiab lwm yam kev taw qhia. Nyob rau theem kev tivthaiv, cov khoom tseem ceeb, deoxynojirimycin, tau raug txheeb xyuas, thiab nws cov txiaj ntsig kev ua haujlwm ntawm PGC-1 tau txheeb xyuas los ntawm cov kev sim ntawm tes thiab ib qho kev tshaj tawm dual-luciferase.

Cov lus xaus yog raws li nram no:

Mulberry twig alkaloids txhim kho lub raum kev ua haujlwm thiab txo lub raum tubular puas thiab fibrosis hauv cov nas uas muaj kab mob raum ntev yam tsis muaj kev cia siab rau cov teebmeem hypoglycemic. Cov txheej txheem cuam tshuam nrog kev ua kom PGC-1, rov ua kom cov kua qaub oxidation muaj peev xwm thiab mitochondrial homeostasis, txo cov lipid deposition, thiab kho lub raum tubular cell muaj nuj nqi los ntawm lub zog metabolism. Txoj kev tshawb no yog thawj zaug kom paub meej tias mulberry twig alkaloids muaj cov nyhuv nephroprotective ncaj qha, muab lub tswv yim tshiab rau lub zog metabolism hauv kev kho mob raum kab mob thiab lub hauv paus tseem ceeb rau kev kho mob ntawm cov tshuaj ntuj.

Lub tuam txhab kev taw qhia thiab daim ntawv pov thawj tau txais

Shaanxi Yuantai Biotechnology Co., Ltd. tau tsim nyob rau xyoo 2014, feem ntau muab cov tshuaj ntsuab rho tawm, cov khoom siv tshuaj pleev ib ce, cov khoom siv organic, thiab lwm yam. Peb muaj peb tus kheej cov chaw tsim khoom, R & D thiab pab pawg soj ntsuam zoo, thiab muaj cov xwm txheej rau kev txhim kho, ntau lawm, thiab kev ruaj ntseg zoo. Tam sim no, peb tau txais ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA thiab lwm daim ntawv pov thawj. Yog li ntawd, qhov zoo ntawm peb cov khoom yog guaranteed, thiab nws yog peb lub hom phiaj tseem ceeb los coj siab - cov khoom zoo rau cov neeg siv khoom.

Peb ntim​

Peb pab neeg

Hoobkas

Txoj kev them nyiaj

Shipping txoj kev

Cov neeg siv khoom tawm tswv yim

Cim npe nrov: 1-deoxynojirimycin, Tuam Tshoj 1-deoxynojirimycin manufacturers, lwm tus, Hoobkas