Liquiritin

Shaanxi Yuantai Biological Technology Co., Ltd. yog ib qho ntawm feem txhim khu kev qha manufacturers thiab lwm tus neeg ntawm liquiritin nyob rau hauv Suav teb. Nrog kev paub ntau, peb sov siab txais tos koj rau cov lag luam wholesale bulk liquiritin rau muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.

Liquiritin yog ib qho tshwm sim ntawm flavonoid compound feem ntau pom hauv licorice (* Glycyrrhiza * spp.). Vim nws cov antioxidant thiab lwm yam khoom, Liquiritin tau siv dav hauv cov tshuaj pleev ib ce thiab kev noj haus.

Khoom nta

1. Natural Origin: Extracted los ntawm licorice paus, nws yog ib tug lawm derived active flavonoid muaj.

2. Cov Txheej Txheem Txheej Txheem: Cov ntsiab lus tau tsim los ntawm HPLC kev tshuaj xyuas, ua kom cov khoom sib xws thiab ruaj khov.

3. Formulation Compatibility: Haum rau siv hauv dej-raws li, emulsion-raws li, thiab hmoov-raws li tshuab.

4. Yooj yim: Raws li ib txwm muaj thiab tsim nyog rau kev txhim kho cov tawv nqaij thiab cov khoom noj khoom haus ntxiv.

Anti-inflammatory thiab tiv thaiv- ua xua
Nws muaj qhov pom tseeb los tiv thaiv- mob thiab tiv thaiv- kev ua xua thiab tuaj yeem cuam tshuam qhov tshwm sim ntawm kev mob tshwm sim thiab kev tsis haum tshuaj. Nws tswj lub cev tiv thaiv kab mob ua haujlwm thiab txo cov kev tso tawm ntawm cov kab mob inflammatory, yog li txo qhov mob thiab cov tsos mob tsis haum. Clinically, nws yog feem ntau siv los kho bronchial hawb pob, eczema, allergic rhinitis, rheumatoid mob caj dab thiab lwm yam kab mob.

Anti- cov nyhuv ulcer
Nws yog dav siv nyob rau hauv kev kho mob ntawm gastric ulcer thiab duodenal rwj. Nws tuaj yeem ua rau muaj kev tiv thaiv ntawm lub plab mucosa, txhawb kev kho thiab rov tsim dua ntawm plab hnyuv, thiab txo qhov tshwm sim thiab nthuav tawm ntawm qhov txhab mob. Tsis tas li ntawd, nws tuaj yeem txo qhov mob thiab tsis xis nyob los ntawm acid reflux.

antiviral nyhuv
Nws muaj qee yam cuam tshuam rau ntau yam kab mob, tshwj xeeb tshaj yog cov kab mob xws li kab mob siab B (HBV) thiab tib neeg kev tiv thaiv kab mob (HIV). Nws tuaj yeem cuam tshuam qhov kev rov ua dua thiab kev loj hlob ntawm cov kab mob thiab txo qhov kev pheej hmoo ntawm kev kis kab mob. Clinically, nws feem ntau siv los kho cov kab mob xws li kab mob siab B thiab AIDS.

Kev tiv thaiv daim siab
Nws tuaj yeem ua kom cov haujlwm ntawm cov enzymes antioxidant, txo cov dawb radical puas rau daim siab hlwb, thiab tiv thaiv daim siab. Nws kuj tseem tuaj yeem txhawb kev tsim kho dua tshiab thiab kho lub siab lub hlwb thiab txhim kho daim siab ua haujlwm. Clinically, nws yog feem ntau siv los kho tus kab mob siab, kab mob siab ntev, daim siab fibrosis thiab lwm yam kab mob.

Tswj ntshav siab
Nws tuaj yeem cuam tshuam kev ua haujlwm ntawm angiotensin-hloov enzyme (ACE), yog li txo qis kev tsim cov angiotensin II, dilating cov hlab ntsha thiab txo cov ntshav siab. Nws tseem tuaj yeem txhawb kev tso zis sodium, txo cov dej thiab sodium tuav hauv lub cev, thiab txo cov ntshav siab. Clinically, nws yog feem ntau siv los kho cov kab mob xws li kub siab thiab kab mob plawv.

Anti-oxidize nyhuv
Nws muaj cov nyhuv antioxidant muaj zog, tuaj yeem cuam tshuam cov dawb radicals, txo cov cell teb rau oxidative kev nyuaj siab, thiab tiv thaiv cell aging thiab puas. Clinically, nws feem ntau siv los tiv thaiv thiab kho Alzheimer's kab mob, tawv nqaij laus, mob qog noj ntshav thiab lwm yam kab mob.

Lwm cov haujlwm
Tsis tas li ntawd, nws kuj muaj ntau yam tshuaj ua haujlwm xws li tshuaj tua kab mob, txhawb kev zom zaub mov, thiab tiv thaiv - mob ntshav qab zib. Nws tuaj yeem cuam tshuam kev loj hlob thiab kev loj hlob ntawm cov qog hlwb, muaj qee yam inhibitory cuam tshuam rau cov kab mob, kab mob, fungi, thiab lwm yam, tuaj yeem txhawb lub plab zom mov, plab zom mov thiab nqus, txo cov ntshav qab zib, thiab ua lub luag haujlwm hauv kev kho mob ntshav qab zib.

Khoom noj khoom haus additive teb:
Liquiritin yog ib yam khoom qab zib uas muaj qab zib zoo ib yam li qab zib, muaj calories tsawg, thiab muaj kev cuam tshuam tsawg rau cov ntshav qab zib. Yog li, liquiritin yog siv los ua cov khoom noj ntxiv rau cov khoom qab zib thiab txhim kho nws saj. Nws tuaj yeem siv rau hauv cov khoom qab zib, biscuits, dej haus, zom cov pos hniav thiab lwm yam khoom noj kom tsw thiab qab zib.

Field of Traditional suav tshuaj:
Hauv thaj chaw ntawm cov tshuaj suav tshuaj, liquiritin yog ib qho khoom siv tshuaj suav tshuaj thiab siv dav hauv ntau yam kev kho mob. Nws feem ntau siv los kho cov kab mob ua pa xws li mob ntsws thiab mob ntsws, thiab tuaj yeem txo cov tsos mob xws li hnoos thiab mob caj pas. Tsis tas li ntawd, liquiritin kuj tseem siv los kho cov kab mob hauv plab hnyuv xws li mob plab, plab zom mov, tsis muaj zog spleen thiab plab. Nws kuj tseem muaj cua sov- tshem tawm, tshem tawm, tshem tawm, tiv thaiv- kis kab mob thiab lwm yam teebmeem, thiab tseem siv los kho qee yam kab mob sib kis.

Pharmaceutical npaj teb:
Nws yog ib qho ntawm cov khoom xyaw tseem ceeb hauv ntau cov tshuaj npaj. Vim nws cov tshuaj tiv thaiv- mob, tiv thaiv- ua xua, tshuaj tiv thaiv- kis kab mob thiab lwm yam teebmeem, liquiritin feem ntau siv rau hauv kev npaj tshuaj tiv thaiv- kis kab mob, tshuaj tiv thaiv- tshuaj tsis haum, tshuaj tiv thaiv - tshuaj tiv thaiv kab mob thiab lwm yam tshuaj. Piv txwv li, liquiritin yog siv los ua cov khoom siv hauv qee cov tshuaj rau kev kho mob ntawm cov kab mob xws li kab mob siab B thiab AIDS.

Cosmetics teb:
Raws li cov khoom xyaw ntuj, nws muaj cov tshuaj tua kab mob antioxidant thiab tiv thaiv - mob, yog li nws tau siv dav hauv cov tshuaj pleev ib ce. Nws txhim kho daim tawv nqaij smoothness thiab elasticity, txo qhov tsim ntawm wrinkles thiab tsaus me ntsis, thaum muaj ib tug calming thiab soothing nyhuv ntawm cov tawv nqaij rhiab heev. Nws feem ntau tshwm sim hauv cov khoom tu tawv nqaij, lub ntsej muag lub ntsej muag, tshuaj pleev ib ce, essences thiab lwm yam khoom.

Haus dej:
Nws kuj yog feem ntau siv hauv dej haus. Nws tuaj yeem siv los ua dej haus xws li licorice tshuaj yej thiab licorice qhov ncauj kua, uas tuaj yeem pab txo qis hauv caj pas, tshem tawm cov cua sov thiab tshem tawm toxins, thiab ua kom ua pa. Tsis tas li ntawd, nws kuj yog siv los ua qee yam dej qab zib rau kev noj qab haus huv, xws li dej qab zib uas txhawb lub plab thiab tiv thaiv daim siab.

Cov ntawv thov kev lag luam pom zoo

· Cov khoom siv tawv nqaij Brightening
·Anti-Kev laus Formulations
· Botanical Tshuaj pleev ib ce
·Nroj-raws li cov khoom ntxiv
· Cov khoom siv tshuaj ntsuab

Kev mob qog nqaij hlav hauv plab (CRC) yog qhov mob hnyav heev thoob plaws ntiaj teb uas muaj teeb meem loj hauv kev kho mob; Cov kev kho mob uas twb muaj lawm tseem ntsib qee yam kev txwv. Raws li cov nroj tsuag tshuaj, *Glycyrrhiza uralensis* (licorice) tau txais kev saib xyuas ntau hauv xyoo tas los no, nrog rau nws cov ntsiab lus tseem ceeb ntawm flavonoid -Liquiritin- tau lees paub tias muaj peev xwm kho tau zoo.

Ib txoj kev tshawb fawb luam tawm nyob rau hauv *Phytomedicine* (IF 6.7, Q1) systematically soj ntsuam cov mechanisms ntawm kev txiav txim ntawm licorice extracts thiab lawv cov active Cheebtsam nyob rau hauv cov ntsiab lus ntawm mob qog noj ntshav. Siv High-Kev Ua Haujlwm Liquid Chromatography (HPLC) kev soj ntsuam, txoj kev tshawb fawb tau txheeb xyuas xya lub ntsiab lus tseem ceeb hauv licorice, ntawm cov Liquiritin tau raug hu ua cov khoom tseem ceeb. Qhov kev tshuaj ntsuam tau qhia tias Liquiritin yuav tsom mus rau ntau yam qog nqaij hlav-cov protein sib txuas- suav nrog TP53, STAT3, SRC, thiab PIK3CA- thiab feem ntau hloov kho cov kev taw qhia xws li MAPK, PI3K-Akt, thiab apoptosis.

Los ntawm molecular docking thiab dynamics simulations, Liquiritin tau pom ib tug ruaj khov affinity affinity rau TP53 protein, tswj cov txheej txheem kev ncaj ncees ntawm cov uas ua complex ntawm ntau hydrogen bonds. * Hauv vitro * kev sim ntawm tes tau pom tias Liquiritin cuam tshuam qhov kev loj hlob ntawm SW480 cov qog nqaij hlav hauv plab; Nyob rau hauv tas li ntawd, nws suppressed lawv clonogenic muaj peev xwm, tsiv teb tsaws, thiab invasion peev xwm, thaum tseem inducing apoptosis. Mechanistically, Liquiritin tau pom los txo qis kev qhia ntawm kev ntxeem tau -cov proteins uas muaj feem xyuam, xws li MMP-1, MMP-3, thiab MMP-9.

Hauv * hauv vivo* tsiaj kev tshawb fawb, Liquiritin kev kho mob cuam tshuam kev loj hlob ntawm xenograft qog nyob rau hauv cov nas liab qab, ua pov thawj los ntawm kev txo qis hauv cov qog ntim thiab qhov hnyav. Tsis tas li ntawd, kev soj ntsuam histological ntawm cov qog nqaij hlav qhia txog kev cuam tshuam ntawm cov txheej txheem thiab thaj chaw ntawm necrosis; tshwj xeeb, tsis muaj kev hloov pauv loj hauv lub cev qhov hnyav lossis cov cim qhia ntawm toxicity tau pom. Txoj kev tshawb no qhia tias Liquiritin siv nws cov teebmeem los ntawm kev tswj hwm p53 kev ua haujlwm thiab inhibiting qib phosphorylation ntawm p38 MAPK teeb liab txoj hauv kev, yog li hloov kho qhov kev loj hlob thiab ciaj sia ntawm cov qog hlwb.

Kev tshuaj xyuas dav dav ntawm cov kev tshawb pom no qhia tias Liquiritin yuav ua rau nws sivntau- phiaj los tiv thaiv- cov teebmeem qog nqaij hlavlos ntawm kev hloov kho p53 / p38 MAPK signaling axis. Qhov no muab lub hauv paus kev tshawb fawb muaj zog rau kev siv Liquiritin hauv kev txhim kho cov khoom xyaw ua haujlwm thiab cov nroj tsuag - muab tau cov tshuaj nquag.

Tiv tauj peb rau COA, Cov Qauv & Cov Lus Tshaj Tawm Kawg

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