Sclareol hmoov

Sclareol yog qhov muaj txiaj ntsig zoo ntuj aromatic compitter. Nws yog cov hmoov dawb crystalline muab rho tawm los ntawm cov qia thiab nplooj ntawm Salvia SClare Salvia lossis Rosette Sage), nroj tsuag ntawm Lamiaae tsev neeg. Qhov kev caij luv luv no diterpenoid muaj npe rau nws cov cim muaj ntxhiab tsw qab. Nrog lub ntsiab lus melting ntawm 95 - 105 degree, nws exudes ib qho hloov maj mam amber aroma (zoo li ambergris). Nws aroma yog tus cwj pwm los ntawm qab zib, balsamic accord, ib qho muag heev, ntev ntev, thiab muaj zog, diffused zoo.

Hauv kev lag luam Fragrance, sclareol yog suav tias yog cov khoom siv raw rau cov synthesis ntawm amberegris cov khoom lag luam. Nws yog feem ntau siv los npaj ntuj ambergris hloov xws li sclareolide thiab ambroxol. Nws tseem siv rau hauv cov khoom me me hauv kev tsim cov qauv ntawm qhov siab-} xaus tsw ntxhiab. Nws cov khoom muaj txiaj ntsig uas muaj ntxhiab tsw tau muab pov tseg ib qho kev muaj zog, sib raug zoo, thiab ntev {{{}} kav cov ntxhiab. Ntxiv rau nws cov kev siv ua txuj lom, sclareol muaj tshuaj kho mob hauv tsev kho mob, xws li anti- mob, thiab choleretic thaj chaw. Hauv thaj chaw ua liaj ua teb, nws tuaj yeem siv los tiv thaiv thiab tswj cov qoob loo fwj thiab powdery mildew, thiab muaj cov haujlwm ntawm kev tua kab thiab tswj cov nroj tsuag kev loj hlob kev ua haujlwm.

Cov txheej txheem no siv Sclareol rho tawm nrog cov ntsiab lus dej cawv ntawm 42.6% raws li cov khoom siv raw los tsim cov khoom siv siab (ntau dua lossis sib npaug ntawm cov kauj ruam:

Cov khoom siv raw ua haujlwm:
Noj 30 kg ntawm sclareol extract thiab ntxiv 300 kg ntawm 60% kev daws teeb meem. Do kom huv si kom txog thaum yaj kiag.

Tsawg - kub, crystallization:
Qhov kev daws teeb meem yog pauv mus rau lub freezer thiab khov ntawm -18℃rau 8 teev rau kev txhawb nqa crystallization.

Thawj qhov kev lim cuam:
Ib ob npaug - txheej txheej formtration system muaj daim txhuam cev thiab cov ntawv lim yog siv kom tau txais daj, pob tshab filparent.

Decolorization thiab Purification:
Ntxiv 1.5 kg ntawm activated carbon mus rau filtrate. Tom qab nruam stirring rau 1 teev, lim los ntawm cov ntaub lim dej 120-Mesh lim kom tau txais cov xim tsis muaj xim, cov tshuaj ntsuab.

Thib Ob Crystallization:
Lub filtrate yog diluted mus rau 20% siab thiab do rau 24 teev kom tso cai ua tiav crystallization.

Ua tiav cov khoom lag luam:
a) sau cov muaju dawb siv daim ntaub muaj 120-mesh
b) centrifugal lub cev qhuav dej
c) Lub Tshuab Nqus Qhuav (600 hli, 60 degree, 6 teev)
d) pulverization thiab tshuaj ntsuam
e) Cov khoom tiav ntim khoom

Tus txheej txheem no ua kom muaj cov khoom kawg nrog cov ntsiab lus dej cawv ntau dua los yog sib npaug ntawm kev tswj qhov kub thiab txias thiab siv lub sijhawm ua kom sov, thiab nqus tsev kom qhuav.

1. Antioxidant thiab photoprotreective cuam tshuam
Sclareol muaj cov khoom tseem ceeb antioxidant. Nws cov molecular qauv zoo rau cov maubenges dawb radicals thiab txo cov kev puas tsuaj cellular tshwm sim los ntawm oxidative kev ntxhov siab. Cov kev tshawb fawb pom tau tias cov khoom xyaw no tuaj yeem daws tau cov tawv nqaij- Cov tawv nqaij ua rau tiv thaiv cov nqaij mos los ntawm kev tiv thaiv keratinocytes los ntawm Ros. Hauv cov kev tshawb fawb vitro tau pom tias nws lub peev xwm los kho U0-}} ua rau cov tawv nqaij puas tsuaj.

2. Anti -} mob thiab tawv nqaij tawv
Los ntawm kev tswj hwm lub NF {- κb signing cov lus qhia txog kev hais tawm ntawm pro -}} 6. Cov kev soj ntsuam kev pom tau pom tias kev npaj muaj 0.5-1% Sclareol tuaj yeem txo tus mob epticion hauv cov neeg mob sab nraud (nrog rau kev ua tau zoo ntawm kwv yees li 68%). Nws cov nyhuv tiv thaiv tau yog piv rau 1% hydrocortisone, tab sis tsis muaj qhov tshwm sim hauv hormonal. Lub tshuab ua haujlwm cuam tshuam nrog kev txo cov mast cell degranulation thiab inhibiting histamine tso tawm.

3. Immunomodulatory ua haujlwm
Cov kev tshawb fawb tsiaj tau qhia tias SCLAREOL tuaj yeem txhim kho macrophage phagocytic ua haujlwm (thaum ua kom muaj kev ua haujlwm ntawm TLR4 / MyD88 txoj kev ua haujlwm Hauv tus nas tus kab mob mob khaub thuas qauv, cov thawj coj ntawm Prophylactic nce ntxiv los ntawm 35%, tawm tswv yim nws lub peev xwm uas nws lub peev xwm tsis muaj zog. Txawm li cas los xij, koob tshuaj nyob hauv tib neeg tseem xav tau cov kev sim tshuaj ntsuam los txiav txim.

4. BroD -}} spectrum antimicrobial cov yam ntxwv
Nyob rau hauv vitro tshuaj tua kab mob (siv agar diffusion txoj kev) tau qhia cov hauv qab no:

• Tiv thaiv gram - Tus kab mob muaj txiaj ntsig zoo: inhibits Staphyrococcus aureus (mic}}}}
• Tawm Tsam: Inhibits Candida Albicans Kev Loj Hlob (Inhibition Zone 12.3 ± 0.5 hli)
• Inhibitia cov nyhuv ntawm propionibacterium acces yog zoo dua rau ntawm salicylic acid (p <0.05).

Cov cuab yeej no ua rau nws haum rau kev txhim kho kev kho mob rau pob txuv, thiab thaum siv ua ke nrog tshuaj tua kab mob, nws tuaj yeem txo qhov teeb meem ntawm cov kab mob tsis kam.

1. Skincar Cov Khoom Txhim Kho
As a functional active ingredient, sclareol powder has been widely used in high-end skincare formulations:

• Anti {-}} Kev Laus Khoom: ntawm 0.1-0.5% ntxiv, nws txo cov kev sim tshuaj dawb rau 42% txo qis collagen poob).
• Soothing thiab kho series: thaum siv ua ke nrog Creamides, nws tuaj yeem txo cov dej transepidermal (TENLL) txog li 35%, ua rau nws tsim nyog rau xa ntawv- laser tu.
• SUNSCREEN YOOJ YIM: Txhim kho cov UVA tiv thaiv ntawm SPF cov khoom lag luam thiab cov khoom siv ua ke nrog titanium dioxide txhawm rau txhim kho photostability.

2. Cov Khoom Noj Qab Haus Huv
Nyob rau hauv kev noj haus kev noj haus tshuaj ntxiv, nws muaj peb thaj chaw thov:

• Kev tiv thaiv kev tiv thaiv kab mob: ib hnub twg ntawm 50-100mg tuaj yeem nce nk ntawm cell kev ua si (cov ntaub ntawv sau ua ntej qhia txog 28% nce).
• Kev tswj kev mob ntsws: Rau kev ua mob caj dab, sib xyaw nrog curcumin tuaj yeem txo cov qib ntshav (19% txo qhov piv rau Meverapy).
• Lub plab: Kev tswj hwm cov plab muaj kev sib tw muaj kev sib tw tau yooj yim tuaj yeem ua tau cov tsos mob IB lo txog li 61%.

3. Frontiersiers hauv Pharm duab R & D
Cov Cheeb Tsam Tshawb Nrhiav Tseem Ceeb thiab Kev Ua Haujlwm:

• Neuroproction: Kev txo cov 33% tau ua kom pom nyob hauv Alzheimer tus qauv thiab tau nkag rau theem kuv sim sim.
• Cov Khoom Siv Tshuaj Tshiab: Nanoliposome Encapsulation Technapsulation Technapsulation Technics ua kom qhov ncauj ntawm ncauj rau 68% (piv rau 12% rau API).

Cim npe nrov: Sclareol hmoov, Tuam Tshoj SCLARYOL hmoov chaw tsim tshuaj, cov chaw muag khoom, Hoobkas