Kev piav qhia
kojic acid dipalmitate yog ib yam tshuaj uas muaj cov mis molecular C38H66O6. Nws yog cov hmoov dawb los yog rab koob zoo li siv lead ua thiab feem ntau yog siv los ua cov tshuaj pleev xim dawb hauv cov tshuaj pleev ib ce.
Cov khoom lag luam: Nws yog cov roj-soluble derivative ntawm kojic acid. Nws tsis tsuas yog kov yeej qhov tsis txaus ntawm kojic acid qhov tsis ruaj khov rau lub teeb thiab cua sov thiab cov xim tsis zoo thaum raug hlau ions, tab sis kuj tsis cuam tshuam nrog cov tshuab kom zoo nkauj vim tsis muaj cov pab pawg hydroxyl hauv nws cov qauv molecular. Cov tshuaj tua kab mob, tshuaj pleev thaiv hnub lossis lwm cov khoom xyaw nquag hauv cov khoom tsim hydrogen bonds thiab cuam tshuam rau kev ua tau zoo ntawm cov khoom ntxiv no. Nws muaj zoo heev compounding zog. Raws li ib tug fat-soluble additive nyob rau hauv cov tshuaj pleev ib ce, ntxiv rau kom yooj yim rau formulation, nws kuj yuav ua tau zoo absorbed los ntawm daim tawv nqaij thiab coj zoo moisturizing los rau ntawm daim tawv nqaij.
Kev tu tawv nqaij cov txiaj ntsig ntawm kojic acid dipalmitate
1) Whitening:Kojic acid dipalmitate muaj txiaj ntsig zoo dua li kojic acid hauv inhibiting cov haujlwm ntawm tyrosinase hauv daim tawv nqaij, yog li inhibiting kev tsim ntawm melanin, thiab muaj txiaj ntsig zoo ntawm daim tawv nqaij dawb thiab tiv thaiv tshav ntuj.
2) Kev tshem tawm freckle:Kojic acid dipalmitate tuaj yeem txhim kho cov tawv nqaij pigmentation thiab tuaj yeem tiv thaiv hnub nyoog me ntsis, ncab cov cim, freckles thiab pigmentation.
Kojic Acid Dipalmitate Cosmetic Compounding Guide
Kojic acid dipalmitate yog ib qho nyuaj rau kev koom ua ke rau hauv formulations thiab tuaj yeem yooj yim tsim crystal precipitates. Txhawm rau daws qhov teeb meem no, nws raug nquahu kom ntxiv isopropyl palmitate lossis isopropyl myristate rau cov roj theem uas muaj kojic acid dipalmitate, thiab ua kom sov cov roj theem mus rau 80 degree thiab ua kom sov li 5 feeb kom txog thaum kojic acid. mus txog dipalmitate. Lub palmitate yog yaj tag, ces ntxiv cov roj theem mus rau theem dej thiab emulsify li 10 feeb. Feem ntau tus nqi pH ntawm cov khoom kawg tau txais yog nyob ib ncig ntawm 5.0-8.0.
Cov tshuaj pom zoo ntawm kojic acid dipalmitate hauv tshuaj pleev ib ce yog 1-5%; qhov ntau npaum li cas hauv cov khoom ua kom tawv nqaij yog 3-5%.
Outlook:Kojic acid dipalmitate kev lag luam kev tshawb fawb daim ntawv tshaj tawm txheeb xyuas cov ntaub ntawv kev lag luam ntawm tsib xyoos dhau los thiab kwv yees kev lag luam kev loj hlob yav tom ntej. Raws li kev txheeb cais, thoob ntiaj teb thiab Suav kojic acid dipalmitate kev lag luam yuav muaj kev lag luam loj ntawm 100 lab yuan (RMB) thiab 100 lab yuan nyob rau hauv 2022. Los ntawm kev tsom xam qhov tob ntawm cov qauv kev lag luam, daim ntawv tshaj tawm ua rau lub hom phiaj kwv yees yav tom ntej. hloov pauv kev lag luam ntawm kojic acid dipalmitate. Raws li tsab ntawv ceeb toom, kev lag luam loj ntawm kojic acid dipalmitate yuav tsum ncav cuag 100 lab yuan hauv 2028.
Cov khoom lag luam tus nqi sib txawv, qhov muag ntim thiab kev lag luam sib koom ntawm kojic acid dipalmitate kev lag luam raug tshuaj xyuas los ntawm qhov kev xav ntawm kojic acid dipalmitate cov khoom lag luam; nyob rau hauv cov nqe lus ntawm daim ntawv thov, daim ntawv tshaj tawm soj ntsuam kev lag luam loj thiab kev lag luam loj ntawm kojic acid dipalmitate kev lag luam hauv ntau daim ntawv thov. Kev loj hlob. Tsis tas li ntawd, daim ntawv tshaj tawm suav nrog kev tshuaj xyuas ntawm cov khoom siv raw khoom tseem ceeb thiab cov chaw muag khoom loj hauv kev lag luam sab saud ntawm kojic acid dipalmitate kev lag luam, nrog rau kev soj ntsuam ntawm qhov kev thov, kev muag ntim thiab kev loj hlob ntawm txhua lub lag luam downstream. Daim ntawv tshaj tawm kuj suav nrog kev txheeb xyuas txog kev lag luam ntshuam thiab xa tawm ntawm Tuam Tshoj kojic acid dipalmitate kev ua lag luam, suav nrog kev lag luam ntshuam thiab xa tawm, tus nqi lag luam, thiab kev tshuaj xyuas ntawm cov teb chaws loj thiab xa tawm thiab cheeb tsam. Kev thov tau nce tsis tu ncua.
Kev sim
3.1 Lub hauv paus ntsiab lus: Siv lub sijhawm txawb - methanol thiab 1% acetic acid aqueous tov (10:90) raws li cov kuab tshuaj, ultrasonic extraction, centrifugation, pom nrog 0.45xm lim membrane, thiab txhaj tshuaj rau hauv cov kua chromatograph nruab nrog lub diode array ntes (DAD) rau kev kuaj pom. , Quantification los ntawm cov txheej txheem sab nraud.
3.2 Reagents thiab cov ntaub ntawv: Tshwj tsis yog tias tau teev tseg, tag nrho cov reagents siv yog qib ntsuas. Cov dej yog thawj-chav dej tau teev tseg hauv GB / T 6682.
3.2.1 Methanol: chromatographically ntshiab.
3.2.2 Kojic acid; purity tsis tsawg dua 98%.
3.2.3 Acetic acid.
3.2.41% acetic acid aqueous tov: Siv 10 mL ntawm glacial acetic acid thiab kho qhov ntim rau 1 000 mL.
3.2.5 Txawb theem: methanol: 1% acetic acid aqueous tov - 10:90.
3.2.6 Kojic acid standard stock solution: Yog qhov hnyav 0.1 g (raug rau 0.000 1 g) kojic acid hauv 50 mL beaker, ntxiv 1% acetic acid aqueous daws nws, hloov mus rau 100 mL volumetric hwj, thiab siv 1% acetic acid aqueous tov rau dissolve nws. Dilute cov tshuaj acetic acid aqueous rau lub cim kom tau txais cov txheej txheem kev daws teeb meem nrog kojic acid concentration ntawm 1 000 mg / L. Khaws rau hauv qhov chaw kaw thiab txias rau 3 lub hlis.
3.2.7 Txuj kev ua haujlwm daws teeb meem: Pipette 0.2 mL, 0.5 mL, 1.0 mL, 2.{{10}} mL, thiab 5. lub cim thiab npaj cov txheej txheem kev ua haujlwm daws teeb meem nrog ntau ntawm 0 02 mg / ml., 0.05 mg / mL, 0.1 mg / mL, 0.2 mg / L, thiab 0.5 mg / L .
3.3 Cov cuab yeej thiab cov cuab yeej siv
3.3.1 Kev ua haujlwm siab ua kua chromatograph nruab nrog diode array ntes.
3.3.2 Micro sampler, 10 L.
3.3.3 Ultrasonic nqus tsev vacuum.
Yog koj xav kawm ntxiv, thov hu rausales@sxytbio.com,Nyem qhov no los tiv tauj peb hauv online
