Ntau lab tus tib neeg thoob plaws lub ntiaj teb muaj feem nrog mob ntev, uas muaj qhov cuam tshuam loj rau lawv lub peev xwm mus rau lawv lub neej txhua hnub. Tshawb nrhiav rau hauv cov tshuaj lom neeg uas yuav ua rau kev ua kom mob yog ib qho kev ua kom muaj kev nyab xeeb kom muaj kev nyab xeeb thiab ua tau zoo.Tetrahydropalmatine, tus alkaloid tam sim no nyob rau hauv ob peb hom nroj tsuag, yog ib qho zoo li cov tshuaj uas tau nyiam mloog. Cov lus sau no rho tawm rau hauv cov txheej txheem ntawm kev ua thiab muaj peev xwm ntawm tetrahydropalmatine los pab nrog kev tswj hwm qhov mob.
Tetrahydropalmatine raws li ntuj muaj mob txi
Tetrahydropalmatine(Thp) yog cov khoom siv Bioactive feem ntau muaj nyob hauv cov nroj tsuag nrog rau Corydalis thiab Stephania genera. Cov nroj tsuag no tau siv rau hauv cov kev coj ua tshuaj ib txwm muaj ntau pua xyoo los daws ntau yam kev mob nkeeg, suav nrog kev mob. Niaj hnub nimno scientific nug tau pib nthuav tawm molecular hauv paus rau thp cov khoom analgesic.
Keeb kwm thiab kev siv ib txwm siv
Kev siv ntawm Corydalis cov nroj tsuag muaj cov hnub thp rov qab ntau txhiab xyoo hauv cov tshuaj Suav thiab Korean. Cov kws kho mob yuav muab cov kev npaj ua ntej los ntawm cov nroj tsuag no los daws qhov mob, txhawb kev so kom txaus siab, thiab txhawb nqa kev ua kom zoo. Qhov kev ntsuas keeb kwm ntev ntawm kev siv muab cov kev tshawb fawb pib rau kev tshawb fawb niaj hnub ua rau cov ntawv thov kev xav tau.
Kawm Txog Kev Lom Zem
Nyob rau hauv cov xyoo thev naus laus zis tam sim no, cov kws tshawb fawb tau raug rho tawm thiab kawm thp kom nkag siab zoo dua nws cov khoom siv pharmacological. Cov kev tshawb fawb preclinical tau pom tias yuav muaj peev xwm los daws cov qauv kev mob hauv cov tsiaj txhu hauv cov qauv tsiaj, ua rau nws muaj peev xwm ua tus neeg muaj peev xwm ua piv txwv. Qhov kev tshawb fawb ntawm lub cev ntawm kev tshawb fawb no tau tso rau hauv av rau kev tshawb nrhiav thp lub luag haujlwm hauv cov tswv yim tswj hwm mob.
Cov Cuab Yeej Ntawm Kev Txhim Kho Nrog Tetranthadropalmatine
Kom txaus siab rau castetrahydropalmatineYuav txhawb nqa qhov kev tswj hwm qhov mob, nws yog qhov tseem ceeb kom nkag siab txog nws kev sib cuam tshuam nrog lub cev ua cov tshuab ua kom mob. Thp zoo li ua haujlwm los ntawm ntau cov txheej txheem los cuam tshuam kev nkag siab mob thiab kis.
DOPAMINE RECEPTOR Tes
Ib qho ntawm thawj txoj kev ua tiav nws cov teebmeem yog los ntawm kev sib cuam tshuam nrog dopamine receptors hauv lub hlwb. Thp tau pom tias ua raws li tus thaiv kev ntawm D1 thiab D2 Dopamine receptors. Qhov kev ntsuas no ntawm dopaminergic signaling tej zaum yuav pab rau thp qhov kev ua kom tsis muaj zog thiab sedative cuam tshuam los ntawm ob qho tib si kev xav ntawm qhov mob.
Gaba System res
Kev tshawb fawb tau qhia tias PP kuj tseem tuaj yeem cuam tshuam lub gramma - ineA) system, lub ntsiab inibitory Neurotransmitter network hauv nruab nrab ntawm cov leeg ntshav nruab nrab. Los ntawm kev txhim kho Gaba kev ua si, thp tuaj yeem txhawb kev so thiab txo kev ntxhov siab, uas feem ntau ua raws li cov mob ntev.
Anti -} Inflammatory ua
Qee qhov kev tshawb fawb tau qhia tias Thp muaj ovsesses anti - pob khoom. Mob mob ntev yog ib qho kev pheej hmoo ua rau muaj ntau yam mob, yog li thp lub peev xwm los kho nws qhov mob {{relieving cuam tshuam.
Sib txuas ua ke tetrahydropalmatine nrog lwm yam kev ua piv txwv
ThaumtetrahydropalmatineQhia cov lus cog tseg raws li kev tswj hwm qhov kev tswj hwm qhov mob, cov kws tshawb nrhiav tseem tau tshawb xyuas nws cov peev xwm ua ke nrog lwm cov neeg sawv cev ua kom sib xyaw ua ke. Txoj kev no ua rau muaj kev siv cov teebmeem thiab muaj peev xwm txo cov tshuaj noj uas xav tau ntawm cov tshuaj kho mob.
Muaj peev xwm rau opioid - sparing teebmeem
Ib thaj tsam ntawm kev txaus siab tshwj xeeb yog qhov peev xwm los txo cov kev yuav tsum muaj cov kev cai tswj hwm kev tswj hwm. Los ntawm kev sib xyaw ua ke thp nrog cov tshuaj opioid, nws yuav ua kom muaj kev phom sij txaus ua kom muaj kev phom sij nrog cov kev tsis zoo uas cuam tshuam nrog ntev-} lub sij hawm opioid siv.
Synergy nrog tsis - opioid analgesics
Cov kws tshawb nrhiav tseem tshawb xyuas cov kev cuam tshuam thp qhov kev sib cuam tshuam nrog tsis - opioid mob tus neeg rov qab xws li nsaids thiab acetaminophen. Kev pom muaj hnub ua ntej uas sib txuas nrog cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov tshuaj cuam tshuam nrog cov tshuaj muaj zog.
Tag
Kev tshawb fawb tshiab ntawm tetrahydropalmatine muaj kev cuam tshuam zoo txaus siab rau kev kho mob mob. Tej zaum nws yuav pab tau rau ntau yam kev mob siab vim nws cov txheej txheem ntawm Dopamine, uas suav nrog cov txheej txheem ntawm Dopamine, uas suav nrog Gaba system, thiab anti {{pob khoom. Yuav tsum muaj kev kawm ntxiv rau ntawm Thp qhov kev nyab xeeb thiab kev ua tau zoo hauv tib neeg ua ntej peb tuaj yeem kos cov lus xaus, tab sis cov tshuaj lom zem rau cov lus cog tseg uas yog qhov kev txhaj tshuaj tshiab.
Muaj kuab lom xws li thp muaj lub peev xwm los ua qhov tseem ceeb nyob rau yav tom ntej ntawm kev xaiv kev nyab xeeb thiab siv tau rau cov uas mob ntev. Kev siv ntawm thp nyob rau yav tom ntej mob kho mob yuav nyob ntawm cov txiaj ntsig ntawm kev tshawb nrhiav txuas ntxiv mus rau nws cov yam ntxwv thiab nws cov kev siv.
Tetrahydropalmatineyog ib qho kev cog lus tshiab txoj kev ua haujlwm ntawm kev noj qab haus huv thiab cov chaw nyab xeeb ntawm kev tshawb fawb thaum txhim kho cov khoom tswj xyuas mob mob tshiab. Yog tias koj nyob hauv khw rau tetrahydropalmatine hmoov, mus tsis muaj deb dua li Shaanxi Yuanti biological Technology kev lag luam thiab kev ntseeg tetrahydropalmalmalmalmatormatine chaw tsim khoom. Yog tias koj xav paub txog kev siv ntawm kev siv ntawm kev kho mob, ytbio yog lub tuam txhab kom ntseeg tau vim yog peb txoj kev mob siab rau kom zoo thiab ua kom zoo dua.
Puas yog koj yog lub tuam txhab nutraceutical, cov chaw tsim khoom siv khoom noj khoom haus, khoom noj khoom haus cov khoom noj uas yuav txaus siab rau kev sib xyaw ua ke rau hauv koj cov kab khoom? Hu rau ytbio hnub no ntawmsales@sxytbio.comXav paub ntau ntxiv txog peb TetrualHydrropalmatine hmoov thiab li cas peb tuaj yeem txhawb koj cov kev tawm dag zog tshiab. Raws li lub npe nrov TetrahlalMalmalmatormatormatormator, peb nyob ntawm no los pab koj nqa txiav - kev tswj hwm kev daws teeb meem rau kev ua lag luam.
Cov FAQ
1. Dab tsi yog tetraydropalmatine siv rau?
TetrahyDropalmatine yog berberine alkaloid tau los ntawm cov kev sib ntxiv ntawm ob lub lwg me me ntawm cov pyridine nplhaib pyridine. Nws muaj lub luag haujlwm ua tus neeg sawv cev adrengic, tsis yog - narcotic analgesic thiab kev thaiv kev dopaminicergic. Nws yog berberine alkaloid, ib organic heterotClaclicclic compound thiab ib (s) -7,8,13,14-tetrahydrorgot boberberry. Nws yog ua haujlwm ntsig txog lub palmatine.
2. Dab tsi yog cov kev mob tshwm sim ntawm tetrantmalmatine?
Cov teeb meem paab cov teeb meem kuj tseem muaj. Xeev siab thiab ntuav tau tshaj tawm hauv qee kis, tshwj xeeb thaum cov compound tau noj ntau dua. Lwm cov kev ntxhov siab ntawm cov plab, xws li mob plab tsis xis nyob thiab raws plab, tuaj yeem tshwm sim. Cov kev mob plawv kev mob plab yog qhov tsawg dua tab sis tseem tsis tseem ceeb.
3. Dab tsi yog cov txiaj ntsig ntawm l tetrahydropalmatine?
L - Tetraydropalmatine (THP) Yordalis Yanhusuo Cog, ib qho Tshuaj ntsuab Kauslim. Qhov no sib xyaw ua kom zoo dua cov tsos mob ntawm lub cev thiab ua ntau yam cuam tshuam txog kev ua kom muaj kev cuam tshuam rau hauv nruab nrab ntawm nruab nrab thiab tsis muaj zog. Qhov tseeb, ntau txoj kev tshawb fawb tau tshawb xyuas nws cov antihociceptive, antihyxidant, anti anti anti- kev ua si. Thp muaj cov txiaj ntsig txiaj ntsig zoo thiab ua kom zoo tshaj plaws.
Ntawv Sawv cev
1. Wang, JB, li al. (2019). Tetrathydropalmatine: Lub peev xwm tshiab rau kev kho mob. Phau ntawv sau txog kev mob, 12, 1663-1678.
2. Liu, yl, li al. (2018). Qhov kev cuam tshuam ntawm tetranthadropalmatine hauv cov tsiaj ua qauv ntawm cov neeg mob hnyav thiab mob ntev. Pharmacology, Biochemistry, thiab tus cwj pwm, 171, 30-35.
3. Zhang, H., li al. (2020). TetrathydroGalmategine attenessates neuropathic mob los ntawm kev tswj hwm cov lus qhia ntawm txha caj qaum dorsal horn gaba receptors. Molecular mob, 16, 1744806920930855.
4. Chen, X., li al. (2017). Cov nyhuv antinociceptive ntawm tetrahydropalmatine hauv cov qauv ntawm kev mob mob hauv nas. Cov ntaub ntawv European ntawm Pharmacology, 802, 1-7.
5. Lis, S., li al. (2021). TetrathydroGalmatine ua ke nrog oxycodone rau kev tswj hwm qhov mob posteroperative Postoperative)) Tshuaj Kho Mob, 22 (3), 686-694.
6.Zhao, Y., li al. (2016). TetrathydroGalmatine: ib txoj kev muaj peev xwm tshiab rau kev kho mob ntawm neuropathic mob. Phau ntawv Journal ntawm Ethnopharmacology, 180, 154-161.
