Acacetin, lub ntuj flavonoid compound tau pom nyob rau hauv ntau cov nroj tsuag muaj cov nroj tsuag muaj txiaj ntsig, tau tawm los ua ib tug neeg muaj kev sib tw hauv cov ntshav qab zib kev tshawb fawb. Qhov kev pom zoo no tau mus rau hauv zej zog science vim nws cov tshuaj tiv thaiv muaj peev xwm ua tau txiaj ntsig cov tib neeg muaj ntshav qab zib. Cov kev tshawb fawb tsis ntev los no tau pom nws lub peev xwm los cuam tshuam cov metabolism, thiab tiv thaiv cov ntaub ntawv anccreatic, thiab tiv thaiv cov ntaub ntawv insulin, thiab kev tiv thaiv insulin-illing rau kev tsim kho ntshav qab zib thiab kev kho mob.
Dab tsi yog cov txheej txheem ntawm kev ua ntawm acacetin hauv cov kev cai ntshav ntshav qab zib?
Insulin signaling kev txhim kho
Acacetin qhia tau zoo kawg li lub peev xwm hauv kev txhim kho insulin teeb tsa txoj kev, uas yog qhov tseem ceeb rau kev tswj cov kua qabzib zoo. Kev tshawb fawb tau pom tias Acacetin activates insulin rectrates thiab txhawb nqa cov gluple transporter 4 (glut4) rau lub cell membrane. Tus txheej txheem no cov txheej txheem sib ntxiv nce garlukose hauv cov nqaij pob txha thiab adipose. Kev tshawb fawb tau qhia tau tiasAcacetinKev kho mob tau txhim kho cov insulin rhiab heev los ntawm kev ua siab rau cov protein cuam tshuam nrog hauv insulin signing cascade, suav nrog PI3K / AKT txoj kab kev. Qhov sib xyaw ua ke muaj peev xwm txhim kho Insulin Receptor phosphorylation thiab cov txheej txheem basostasis zoo dua hauv cov ntshav qab zib.
Cov metabolism hatabolism teeb meem
Nyob rau hauv cov ntsiab lus ntawm cov metabolism, Acacetin ua kom muaj cov txiaj ntsig zoo uas ua rau muaj kev tswj hwm Glycemic zoo dua. Qhov sib xyaw ua ke tau pom tias muaj cov enzymes tseem ceeb nrog rau cov piam thaj ntau, xws li gospose -6- phosphateenolpau, yog li txo hepatic qabzed tawm. Ib qho ntxiv, acacetin txhawb nqa glycogen synthesis nyob rau hauv daim siab thiab pob txha nqaij los ntawm kev ua kom ua haujlwm glycogen ntawm glycogen phosphorlinelase kev ua si. Cov teebmeem no ua ke pab tswj cov ntshav kom muaj ntshav khov kho thiab tiv thaiv hyperglycemic ntu hauv qab zib mob ntshav qab zib.
Pancreatic -Cell tiv thaiv
Ib qho ntawm feem ntau qhov tseem ceeb ntawm acacetin tus antidiabetic cov khoom yog nws cov nyhuv tiv thaiv on pancreatic -cells. Qhov sib xyaw ua ke tau pom qhov muaj peev xwm tiv thaiv oxidative kev ntxhov siab-ua kev puas tsuaj rau -cells los ntawm kev ua kom cov tshuaj tiv thaiv kab mob antioxidant. Kev tshawb fawb qhia tau tias Acacetin kev kho kom nce cov enzymes enzymes xws li superoxide dismutase thiab catalase fancreatic nqaij. Tsis tas li ntawd, nws pab tswj kom muaj kev sib kho kom zoo nkauj thiab kev tiv thaiv kev ua kom tsis txhob mob siab thiab tsis muaj qhov tseem ceeb rau kev tsim khoom insulin thiab tso pa tawm.
Accetin cais cov insulin tsis kam thiab rhiab?
Molecular Txoj Kev Tswj Xyuas
AcacetinLub cawv txiv neej tsis kam cuam tshuam nrog cov kev sib cuam tshuam molecular ua rau thaum kawg txhim kho cov tshuaj insulin. Cov compound tau pom tias muaj ntau yam kev kos npe hauv txoj kev kos tsheb, suav nrog lub luag haujlwm AMPK, uas ua lub luag haujlwm ntawm lub cev me me hauv kev siv hluav taws xob thiab cov tshuaj insulin. Kev tshawb fawb qhia pom tias Acacetin ua kom tau txais kev nce siab ntxiv hauv insulin-resistant hlwb los ntawm kev txhawb nqa glut4 kev pab cuam. Ib qho ntxiv, qhov sib xyaw ua ke pab tswj cov mob kho mob uas ua rau cov tshuaj insulmatory tsis kam, xws li tnf- thiab li kev txhim kho cov insulin insulin rhiab ntawm qib molecular.
Kev Tswj Xyuas Hluav Taws Xob Hluav Taws Xob
Lub luag haujlwm ntawm Acacetin hauv kev tswj hwm metabolic tau tshwj xeeb tshaj yog nyob rau hauv cov ntsiab lus ntawm insulin tsis kam. Cov kev tshawb fawb tau pom tias qhov sib xyaw ua kom zoo ntxiv txo qhov kev qhia ntawm cov pro-inflammatory cytokines thiab adipokines uas ua rau cov tshuaj insulin tsis kam. Acacetin kev kho tau pom kom txo qis NF-κB kev ua kom tsawg dua thiab cov lus teb rau kev hloov pauv thiab cov leeg pob txha. Qhov kev tawm tsam no yuav pab rov ua haujlwm thiab txhim kho cov nqaij mos hauv insulin-resistant cov nqaij mos, ua rau nws muaj txiaj ntsig zoo rau kev tswj hwm ntshav qab zib-cuam tshuam.
Adipose nqaij ua haujlwm txhim kho
Acacetin qhia tau cov txiaj ntsig zoo nyob rau ntawm cov nqaij ntshiv muaj nuj nqi, uas yog qhov tseem ceeb rau kev tswj hwm cov insulin rhiab. Cov compound tau pom los txhawb kev noj qab haus huv adipocyte sib txawv thiab muaj nuj nqi, ua rau cov insulin zoo dua hauv cov nqaij muaj rog. Kev tshawb fawb qhia tau tias Acacetin kev kho txhim kho adiponectin zais cia los ntawm adipocytes, ib qho tseem ceeb adipokine uas txhim kho cov tshuaj uas ua kom cov tshuaj insulin. Tsis tas li ntawd, qhov sib txuas ua ke pab tswj cov metabolism lipid hauv tebchaws Lipid, txo cov khoom lag luam lipid uas ua rau cov tshuaj insulin tsis kam.
Cov kev siv acacetin muaj peev xwm acacetin muaj cov mob ntshav qab zib?
Cov ntaub ntawv pov thawj thiab kev tshawb fawb
Kev kho mob ntawm Acacetin ua mob ntshav qab zib yog txaus siab los ntawm ntau cov kev tshawb fawb cov kev tshawb fawb thiab tshawb nrhiav. Kev tshawb nrhiav tau pom tiasAcacetinCov thawj coj tseem ceeb txo qis kev yoo ntshav cov ntshav qab zib thiab kev txhim kho kev ua kom muaj cov qauv ntshav qab zib. Cov kev sim kho mob tau pom tias cov neeg mob acacetin-muaj kev npaj ua kom zoo dua glycemic tswj glycemic tswj glycemic tswj thiab txo HBA1C qib. Cov kev tshawb fawb no tseem qhia tau tias qhov sib xyaw ua ke muaj kev txhawb nqa ncua sijhawm ntev, qhia nws cov peev xwm ua qhov kev xaiv ntshav qab zib ntev.
Kev Kho Mob Muaj Peev Xwm
Kev tshawb fawb tshawb nrhiav kev sib xyaw ua ke ntawm acacetin nrog cov tshuaj ua noj qab zib muaj txiaj ntsig tau pom muaj cov txiaj ntsig zoo. Cov kev tshawb fawb pom tias Acacetin tuaj yeem txhim kho qhov ua tau zoo ntawm cov qauv tshuaj antidimetic thaum muaj peev xwm txo lawv cov tshuaj xav tau. Qhov kev sib xyaw ua cov cim kev tshwj xeeb ntawm kev ua tiav, tshwj xeeb hauv cov ntaub ntawv kho mob ib leeg muab suboptimal cov txiaj ntsig. Cov chaw kuaj mob soj ntsuam tau pom cov kev cuam tshuam zoo thaum Acacetin yog siv nrog Metformin lossis SulfonyLuras, hais txog nws cov peev txheej hauv kev tswj hwm ntshav qab zib.
Kev Siv Tiv Thaiv
Cov ntawv thov kev tiv thaiv ntawm Acacetin hauv kev tswj hwm ntshav qab zib sawv cev rau thaj chaw zoo siab ntawm kev tshawb fawb. Cov kev tshawb fawb tau qhia tias ACACETERIN ntxiv yuav pab tiv thaiv cov ntshav qab zib ntawm cov neeg muaj kev pheej hmoo thiab cov tshuaj insulin zoo. Kev tshawb fawb qhia tau tias qhov sib xyaw muaj peev xwm tiv thaiv pancreatic -cells thiab txo qhov mob ua rau nws muaj txiaj ntsig tshwj xeeb hauv kev tiv thaiv kev mob ntshav qab zib zuj zus. Kev tshawb nrhiav tau ntev ntev yuav muaj txiaj ntsig zoo hauv kev tswj hwm cov kev noj qab haus huv metabolic thiab txo qis kev pheej hmoo ntawm kev tsim cov kab mob ntshav qab zib-cuam tshuam.
Tag
AcacetinUa kom pom muaj peev xwm muaj peev xwm tswj hwm ntshav qab zib los ntawm nws cov multifaceted ntawm cov metabolism, insulin rhiab, thiab pancell tiv thaiv. Qhov sib xyaw muaj peev xwm tswj hwm ntau txoj hauv kev pab ntshav Aatophysiology, sib txuas nrog cov tswv yim rau cov tswv yim kho ntshav qab zib. Kev tshawb fawb ntxiv thiab cov kev kawm soj ntsuam yuav txuas ntxiv mus qhia txog qhov muaj peev xwm ntawm lub ntuj no ua rau mob ntshav qab zib.
Shaanxi yuantai biological Technology Co., Ltd. Peb ua tshwj xeeb hauv cov khoom noj khoom haus noj haus huv (cov tshuaj ntsuab cuam tshuam, thiab creatine cov khoom xyaw (suav nrog daim txhuam cev, retinol, glbutin). Peb ua haujlwm nrog cov khub hauv Europe, America, Southeast Asia, thiab Kaus Lim Kauslim. Nrog lub tsev rau khoom nyob rau hauv Rotterdam rau EU faib khoom thiab npaj rau Asmeskas cov ntaub ntawv ua haujlwm zoo thiab tuav cov ntawv pov thawj nrog rau HACCP, FDA, EU & NMPA. Peb tseem yuav pab Kauslim cov neeg siv nrog KFDA sau npe. Peb lub hom phiaj yog tsim kev sib koom tes ntev ntev nrog cov khoom lag luam zoo thiab kev pabcuam tshaj lij. Txog rau cov lus nug, tiv tauj peb ntawmsales@sxytbio.comlossis {{+86-029-86478251 / +86-029-86119593.
Ntawv Sawv cev
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