Sesamin, ib tug lignin compound, yog ib tug natural antioxidant thiab lub ntsiab active ingredient nyob rau hauv sesame noob los yog noob roj ntawm tsev neeg flax.

Ntxiv rau cov noob hnav los ntawm tsev neeg Flaxaceae, sesamin kuj tau raug cais tawm ntawm ntau hom nroj tsuag, xws li: Asarum los ntawm genus Asarum los ntawm tsev neeg Aristolochiaceae, Zanthoxylum bungeanum los ntawm tsev neeg Rutaceae, Bashan Sesamin kuj tau pom nyob rau hauv Suav tshuaj ntsuab tshuaj ntsuab. xws li Zanthoxylum bungeanum, Cuscuta sinensis, thiab Cinnamomum camphora.

Txawm hais tias cov nroj tsuag no muaj cov sesamin, lawv cov ntsiab lus tsis siab npaum li cov noob hnav noob ntawm tsev neeg flax. Cov noob noob hnav muaj li ntawm {{0}}.5% mus rau 1.0% lignans, qhov tseem ceeb tshaj plaws yog sesamin, uas suav txog li 50% ntawm tag nrho cov sib xyaw lignan.

【English name】: Sesamin

【CAS Number】: CAS 607-80-7

【Botanical Source】: Sesamum indicum DC.
【Part Use】: Noob

【Appearance】: Fine Grey Dawb rau dawb siv lead ua hmoov

【Specifications】: Sesamin 10%, 50%, 60%, 80%, 90%, 98% los ntawm HPLC

【Extraction Method】:

Txoj kev sib cais thiab rho tawm ntawm sesamin feem ntau yog muab faib ua ob pawg: ib qho yog siv cov kuab tshuaj organic xws li methanol, ether, thiab lwm yam kom ncaj qha rho sesamin los ntawm cov noob hnav roj, thiab tom qab ntawd recrystallize thiab purify nws; lwm qhov yog siv cov distillation qis ntawm cov noob hnav roj, thiab tom qab ntawd ua cov distillate Molecular distillation, resin adsorption thiab lwm yam kev kho mob. Nrog rau kev ua kom tob zuj zus ntawm kev tshawb fawb ntawm sesamin, qhov yuav tsum tau ua rau purity, kev tsim khoom thiab kev ruaj ntseg ntawm cov khoom sesamin kuj tau nce siab dua. Cov zej zog thoob ntiaj teb nyiam siv hom thib ob ntawm txoj kev thiab ua ntej kev kho lub cev ntawm cov noob hnav roj. kom tsis txhob muaj kab mob los ntawm cov kuab tshuaj organic.

【Variety sib txawv】:

Cov ntsiab lus sesamin ntawm cov noob hnav los ntawm ntau lub hauv paus pib sib txawv heev. Muab piv 42 hom sesame noob tawg los ntawm Tuam Tshoj, Mexico, Colombia, Nyab Laj, Afghanistan thiab lwm qhov chaw, nws tau pom tias cov ntsiab lus sesamin nyob rau hauv cov roj sesame muaj li ntawm 0.07% mus rau {{5. }}.61%, nrog tus nqi nruab nrab ntawm 0.36%. Cov ntsiab lus ntawm sesamin qis tshaj plaws yog nyob rau hauv cov qauv ntawm cov noob dub nrog cov roj cov ntsiab lus ntawm 44.5%, thaum lub siab tshaj plaws cov ntsiab lus sesamin yog nyob rau hauv cov noob dawb qauv nrog cov roj cov ntsiab lus ntawm 55.1%. Ntawm cov noob hnav noob qoob loo loj hlob ntawm tib tsob nroj, cov noob hnav noob loj hlob hauv qab muaj cov ntsiab lus sesamin qis tshaj. Ntawm qhov tsis sib xws, cov noob txiv ntoo loj hlob ze rau sab saud muaj cov ntsiab lus ntau dua sesamin. Cov txiaj ntsig kev tshawb fawb no qhia tias yog tias sesamin tau muab rho tawm, tsis yog tsuas yog ntau yam, tab sis kuj tseem cuam tshuam ntawm keeb kwm thiab lub sijhawm loj hlob yuav tsum tau muab sau tseg thaum xaiv cov khoom.

【Function】:

(1) Antioxidant nyhuv:

Sesamin tuaj yeem tshem tawm cov peroxide ntau dhau, hydroxyl dawb radicals, thiab cov organic dawb radicals hauv lub cev. Kev tsim thiab tshem tawm cov pa dawb radicals hauv tib neeg lub cev yog nyob rau hauv qhov sib npaug. Yog tias qhov nyiaj tshuav no tawg, ntau yam kab mob yuav ua raws. Los. Cov kev tshawb fawb tau pom tias sesamin tuaj yeem ua rau muaj kev ua haujlwm ntawm cov dawb radical scavenging enzymes, inhibit oxidative kev ntxhov siab, txo cov tsim ntawm oxygen dawb radicals, thiab ua lub luag haujlwm tiv thaiv hauv lub cev. Hauv kev sim tshuaj antioxidant hauv vitro, nws tau pom tias sesamin muaj peev xwm zoo antioxidant tiv thaiv DPPH dawb radicals, hydroxyl dawb radicals, superoxide anion dawb radicals thiab ABTS dawb radicals, thiab nyob ze rau kev ua haujlwm antioxidant ntawm cov antioxidant VC. Ib qho antioxidant zoo dua.

(2) Anti-inflammatory nyhuv:

Inflammation yog txhais raws li ib tug series ntawm kev tiv thaiv cov lus teb ntawm lub cev nqaij daim tawv nrog vascular systems rau ua puas yam. Kev mob tshwm sim tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lub cev xws li kev loj hlob ntawm tes thiab cov metabolism, ua rau muaj kev hloov pauv pathological hauv tib neeg cov ntaub so ntswg. Kev mob tshwm sim kuj feem ntau ua rau muaj qhov txawv txav ntawm tus lej thiab kev ua haujlwm ntawm osteoclasts, ua rau cov pob txha ntau dhau thiab ua rau muaj ntau yam kab mob osteolysis, nrog rau mob caj dab, mob osteolysis, aseptic loosening ntawm cov pob qij txha, thiab kab mob periodontal. Yan et al. Cov kev tshawb fawb tau pom tias sesamin tuaj yeem cuam tshuam kev sib txawv ntawm osteoclast thiab cov pob txha resorption, txo qhov tsim cov cytokines pro-inflammatory, inhibit osteoclast sib txawv, thiab txo LPS-induced osteolysis. Cov txheej txheem tshwj xeeb yuav yog tias sesamin inhibits ERK. thiab NF-κB kev taw qhia txoj hauv kev inhibit osteoclast sib txawv thiab cov gene qhia tshwj xeeb. Yog li ntawd, sesamin tej zaum yuav yog ib qho tshuaj muaj peev xwm rau kev kho mob osteolysis.

(3) txo cov roj (cholesterol) phem:Kev nce ntshav hauv cov ntshav triglycerides thiab cov roj cholesterol yog qhov tseem ceeb hauv kev ua rau atherosclerosis thiab kab mob plawv thiab cerebrovascular. Hauv kev sim ntawm cov teebmeem ntawm sesamin ntawm cov ntshav lipids, ntshav qab zib, thiab kho vascular remodeling nyob rau hauv cov nas noj nrog cov rog thiab siab qab zib, nws tau pom tias sesamin muaj cov nyhuv hypolipidemic, thiab nws cov txheej txheem cuam tshuam nrog sesamin nce lipase kev ua, nce rog. metabolism, thiab txo cov rog deposition. Hauv kev sim tshuaj ntsuam xyuas ntawm sesamin siv rau cov neeg mob hypercholesterolemia, nws tau pom tias tag nrho cov roj (cholesterol) tag nrho ntawm pawg sesamin txo qis los ntawm qhov nruab nrab ntawm 8.5%, cov ntsiab lus qis lipoprotein tsawg (LDL-C) cov ntsiab lus poob los ntawm qhov nruab nrab ntawm 14. %, thiab high-density lipoprotein cholesterol theem txo qis los ntawm qhov nruab nrab ntawm 14%. (HDL-C) nce los ntawm qhov nruab nrab ntawm 4%, cov nyhuv yog ze rau cov tshuaj tiv thaiv lipid thiab muaj kev nyab xeeb thiab tsis muaj kev phiv.

(4) Tiv thaiv lub siab

Cov metabolism ntawm sesamin feem ntau tshwm sim hauv daim siab. Sesamin tuaj yeem tswj hwm cov dej cawv thiab cov roj metabolism hauv cov enzymes, txhawb cov metabolism hauv ethanol, thiab txhawb cov fatty acid beta oxidation, yog li txo qhov kev puas tsuaj ntawm ethanol rau lub siab thiab tsub zuj zuj ntawm cov rog hauv daim siab.

(5) Antihypertensive nyhuv

Sesamin tuaj yeem nce qhov concentration ntawm NO hauv tib neeg cov hlab ntsha endothelial thiab inhibit qhov concentration ntawm ET-1 hauv cov hlwb endothelial, yog li inhibiting thiab tswj cov ntshav siab [23]. Tsis tas li ntawd, sesamin tuaj yeem txhim kho hemodynamics hauv nas nrog raum ntshav siab, thiab nws cov txheej txheem yuav cuam tshuam nrog nws cov tshuaj tiv thaiv oxidation, nce myocardial NO thiab txo ET-1.

COA:

Yuav ua li cas xaiv sesamin?

1. Cov khoom xyaw tau sau meej meej

Xyuas seb cov ntsiab lus ntawm sesamin ntawm cov khoom xyaw yog cim kom meej. Raws li cov kev cai ntawm Food and Drug Administration ntawm Ministry of Health thiab Welfare, sesamin yog txawv los ntawm sesame extract. Tsuas yog thaum cov sesamin concentration nce mus txog ntau dua 97% nws tuaj yeem hu ua sesamin; yog tias cov sesamin concentration tsawg dua 97%, nws tuaj yeem hu ua sesamin. belongs rau sesame extract.

2. txaus noj sesamin

Ua raws li cov lus qhia ntawm koj tus kws kho mob lossis kws kho mob noj zaub mov lossis ntsuas koj tus kheej qhov xwm txheej kom noj sesamin txaus; Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (Food and Drug Administration) tau teev tseg tias qhov kev txwv txhua hnub ntawm sesamin yog 15 mg.

3. Ua ke nrog cov khoom xyaw ua ke

Ntxiv nrog rau kev ntxiv sesamin txaus, yog tias nws tuaj yeem ua ke nrog kev so thiab pw tsaug zog-pab cov khoom xyaw, tag nrho cov txiaj ntsig tuaj yeem txhim kho tau zoo, xws li: GABA, tryptophan, vitamins (vitamin B6, B12 thiab vitamin D), cog extracts ( asparagus extract), chamomile extract), magnesium thiab calcium, thiab lwm yam.

4. Cov khoom lag luam muaj daim ntawv tshuaj xyuas, uas ua kom muaj kev thaj yeeb nyab xeeb

Ua ntej yuav "Sesamin" cov khoom, koj tuaj yeem paub tseeb tias puas muaj cov ntaub ntawv tshuaj xyuas txog cov khoom lag luam, uas yuav tsum suav nrog cov txiaj ntsig kev nyab xeeb thiab tsis pom zoo xws li cov hlau hnyav, cov khoom siv yas, thiab cov tshuaj tua kab kom zoo thiab kev nyab xeeb ntawm cov khoom.

Thaum twg yog lub sijhawm zoo tshaj plaws los noj sesamin? Koj yuav tsum noj sesamin ua ntej mus pw?

Txij li thaum sesamin yog cov khoom muaj roj-soluble, lub sijhawm zoo tshaj plaws los noj sesamin yog tom qab noj mov kom zoo dua. Yog tias koj xaiv cov khoom sib xyaw sesamin thiab xav txhim kho cov nyhuv pw tsaug zog, nws raug nquahu kom haus nws 1 teev ua ntej yuav mus pw.

Contraindications thiab phiv ntawm sesamin

Cov neeg tsis haum rau cov noob hnav: Cov neeg ua xua rau cov noob hnav lossis cov txiv ntoo yuav tsum tsis txhob noj sesamin.

Cov poj niam cev xeeb tub los yog pub niam mis: Thov nrog ib tus kws kho mob ua ntej noj.

Noj cov tshuaj steroids thiab cov tshuaj hypolipidemic: Sesamin tuaj yeem txo cov ntshav lipids, yog li cov neeg uas noj cov tshuaj steroids, cov tshuaj hypolipidemic lossis lwm yam tshuaj txo cov roj cholesterol yuav tsum sab laj nrog kws kho mob ua ntej siv.

Anticoagulant-related tshuaj: Sesamin tuaj yeem cuam tshuam rau platelet aggregation thiab coagulation, yog li cov neeg uas noj tshuaj anticoagulant lossis tshuaj antiplatelet yuav tsum sab laj nrog kws kho mob ua ntej siv.

Kev sib cuam tshuam tshuaj: Txij li cov sesamin tuaj yeem txhim kho daim siab metabolism, cov neeg siv tshuaj ntev ntev yuav tsum sab laj nrog kws kho mob ua ntej siv sesamin kom tsis txhob muaj kev cuam tshuam tshuaj.

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