Taw qhia:
Baicalin yog ib hom flavonoid compound muab rho tawm los ntawm cov cag qhuav ntawm Scutellaria baicalensis Georgi. Nws yog lub teeb daj hmoov nrog iab saj ntawm chav tsev kub. Insoluble hauv methanol, ethanol, acetone, me ntsis soluble hauv chloroform thiab nitrobenzene, yuav luag insoluble hauv dej, soluble hauv kub acetic acid. Thaum ferric chloride tshwm ntsuab, thaum lead acetate tsim txiv kab ntxwv precipitate. Soluble nyob rau hauv alkali thiab ammonia, nws yog daj thaum xub thawj, thiab sai sai yuav dub xim av.
Nws muaj cov haujlwm tseem ceeb ntawm cov kab mob lom, xws li tshuaj tua kab mob, diuretic, tshuaj tiv thaiv kab mob, txo cov roj cholesterol, tiv thaiv thrombosis, txo kev mob hawb pob, txo cov hluav taws thiab detoxification, hemostasis, tshuaj tua kab mob, tshuaj tiv thaiv kev ua xua thiab spasmolytic nyhuv.
Nws kuj yog ib qho tshwj xeeb inhibitor ntawm daim siab sialoenzyme hauv cov tsiaj nyeg, muaj cov txiaj ntsig ntawm kev tswj qee cov kab mob, thiab muaj zog physiological nyhuv ntawm cov tshuaj tiv thaiv kab mob.
Nws yog tsuas yog siv rau kev kho mob ntawm dampness, kub, hauv siab kev nyuaj siab thiab ntuav, dampness thiab kub filling, raws plab thiab jaundice, ntsws kub hnoos, kub kub thiab nqhis dej, ntshav kub ntuav, carbuncle o mob tshuaj lom, nyob tsis tswm fetus. Tsis tas li ntawd, baicalin tuaj yeem nqus tau cov kab hluav taws xob ultraviolet, tshem tawm cov pa oxygen dawb radicals thiab inhibit qhov tsim ntawm melanin, uas yog cov khoom siv zoo nkauj zoo nkauj.
Muaj nuj nqi
Antioxidant muaj peev xwm
Baicalin yog ib qho antioxidant zoo, uas tuaj yeem tiv thaiv oxidation cov tshuaj tiv thaiv los ntawm oxygen dawb radicals xws li superoxide anion thiab catalase. Txhawm rau kom ua tiav lub hom phiaj ntawm kev tshem tawm cov dawb radicals ntau dhau hauv cov hlwb thiab tiv thaiv cov hlwb los ntawm kev puas tsuaj hauv hypoxia / reoxygenation. Hauv kev xaus, baicalin tuaj yeem tsis tsuas yog tshem tawm cov dawb radicals nyob rau theem pib saw, tab sis kuj ncaj qha ntes cov dawb radicals nyob rau hauv cov dawb radical cov tshuaj tiv thaiv saw, thaiv cov dawb radical cov tshuaj tiv thaiv, thiab ua si ob txheej txheej hauv kev tiv thaiv thiab rhuav tshem cov saw. .
Antibiosis
Baicalin plays lub luag haujlwm tiv thaiv kab mob hauv ntau yam, suav nrog kev ua kom lub cev tsis muaj zog, tiv thaiv kev tsim cov biofilms, txo qhov mob, rhuav tshem cov kab mob phem, inhibiting kab mob enzymes, txo cov kab mob endotoxins, thiab txo cov tshuaj tiv thaiv.
Cov kev tshawb fawb tam sim no tau pom tias baicalin muaj qhov cuam tshuam rau cov kab mob gram-positive thiab gram-negative. Piv txwv li, nyob rau hauv bovine mastitis tshwm sim los ntawm E. coli, baicalin txuas mus rau E. coli cell phab ntsa, txo cov stability ntawm cov kab mob, txhim kho permeability ntawm phab ntsa cell, thiab nws thiaj li ua rau cov kab mob tuag.
Hypolipidemic ntshav siab
Baicalin tuaj yeem ua lub luag haujlwm hauv kev txo cov ntshav lipids los ntawm kev txo cov ntsiab lus ntawm cov ntshav lipids. Qhov laj thawj tseem ceeb yog tias baicalin tuaj yeem cuam tshuam cov synthesis thiab nqus cov roj cholesterol, yog li txo cov ntsiab lus ntawm cov cholesterol hauv cov ntshav thiab txhim kho cov tsos mob ntsig txog kab mob plawv. Baicalin tseem tuaj yeem ua lub luag haujlwm hauv kev txo cov ntshav siab. Qhov laj thawj tseem ceeb yog tias baicalin tuaj yeem cuam tshuam cov hlab ntsha thiab yog li ua lub luag haujlwm hauv kev txo cov ntshav siab. Tsis tas li ntawd, baicalin tseem tuaj yeem txhawb kev nthuav dav ntawm cov hlab ntsha thiab txhim kho cov ntshav khiav, yog li pab tiv thaiv qhov tshwm sim ntawm kub siab.
Anti-inflammatory thiab tswj kev tiv thaiv kab mob
Ntawm tag nrho cov physiological teebmeem ntawm baicalin, anti-inflammatory thiab kev tiv thaiv kab mob yog tshwj xeeb tshaj yog tseem ceeb, xws li: mob hawb pob, mob pancreatitis, mob ntsws mob, mob siab mob, daim siab fibrosis, hnub dermatitis, periodontitis, thiab lwm yam. Baicalin feem ntau yuav txo tau cov inflammatory kev puas tsuaj. ntawm cov ntaub so ntswg thiab tswj qee lub cev tiv thaiv kab mob kom zais cytokine interferon los ua lub luag haujlwm tiv thaiv kab mob. Baicalin tuaj yeem ua lub luag haujlwm hauv kev tiv thaiv kab mob los ntawm kev txhawb nqa apoptosis, thiab cov pov thawj rau qhov no feem ntau yog los ntawm inhibition ntawm baicalin ntawm cov qog hlwb.
Daim ntawv thov
Ayam kab mobkev kho mob
Nws yog siv rau purging hluav taws thiab detoxifying, hemostasis, thiab antifetal siv. Nws muaj broad-spectrum antibacterial effect, thiab tseem muaj txiaj ntsig zoo rau lub gallbladder, anti-inflammatory, anti-allergic, antipyretic, detoxifying, diuretic, thiab antihypertensive. Nws yog siv nyob rau hauv kev kho mob ntawm tus kab mob siab kab mob, thiab muaj ib tug zoo ntxim rau txo glutamic-pyruginic transaminase thaum lub sij hawm kev ua si kab mob siab. Nws kuj tseem siv rau hauv kev kho mob stroke thiab tuag tes tuag taw, uas tuaj yeem txo cov hlab ntsha tsis ua haujlwm, ua kom cov ntshav hauv hlwb, txhim kho cov ntshav-hlwb barrier permeability thiab tiv thaiv platelet agglutination los ntawm adenosine phosphate.
Clinicically
Kev kho mob ntawm kab mob siab, mob jaundice thiab kab mob siab ntev, mob plab kab mob, kab mob lead lom thiab lwm yam kab mob
Cosmetics
Baicalin tseem tuaj yeem nqus tau cov kab hluav taws xob ultraviolet, tshem tawm cov pa oxygen dawb radicals, thiab inhibit tiam ntawm melanin, yog li nws tuaj yeem siv rau hauv cov tshuaj thiab tshuaj pleev ib ce, thiab yog cov khoom siv zoo nkauj zoo nkauj.
Kev npaj ntawm baicalin
Cov txheej txheem kev npaj ib txwm muaj ntawm baicalin suav nrog methanol lossis ethanol extraction, concentration, phaj thiab thav duab filtration, acid nag lossis daus thiab recrystallization, thiab lwm yam, uas muaj cov nram qab no shortcomings: 1. Environmental pollution: Nyob rau hauv cov txheej txheem npaj yuav tsum tau siv ntau cov organic. cov kuab tshuaj xws li methanol, ib puag ncig muaj kuab paug, kev nyab xeeb tsis zoo; 2. Cov nqi tsim khoom lag luam yog siab dhau: cov txheej txheem kev lag luam uas twb muaj lawm yog cumbersome thiab complex, thiab cov cua sov reflux extraction yuav tsum tau muab rho tawm peb zaug, txhua zaus 2h, tsawg kawg yog rau teev, lub voj voog ntau lawm ntev, cov khoom poob. yog loj, thiab cov khoom kawg cov ntsiab lus ntawm baicalin tsuas yog ncav cuag 80%.
Lub invention muaj feem xyuam rau ib txoj kev npaj ntawm baicalin, uas yog characterized nyob rau hauv hais tias:
Cov kauj ruam npaj muaj xws li:
Kev npaj: Xaiv cov khoom zoo scutellaria baicalensis ua raw khoom, crushed, los ntawm 10 ~ 40 mesh sieve;
Extraction: boiling dej pub stirring reflux extraction 2 zaug, khoom-kua piv ntawm 1∶8 ~ 15;
Lim thiab concentration: lim cov extract ntawm kauj ruam 2, mloog zoo rau cov filtrate nyob rau hauv lub siab txo, kom txog rau thaum lub tshwj xeeb gravity ntawm cov concentrated paste yog 1.1 ~ 1.3;
Caw dej cawv: cov concentrated paste tau txais nyob rau hauv kauj ruam 3 yog ntxiv nrog 3 mus rau 5 npaug ntawm cov pa roj carbon tsawg, rhuab ntawm 4 0 mus rau 70 degree rau 0.5h, lim, thiab cov lim yog condensed nyob rau hauv siab kom rov zoo. cawv;
Acid nag lossis daus: Cov kua qaub uas tau txais hauv qib 4 tau hloov kho rau pH 1 ~ 2 nrog 1M acid tov, tom qab ntawd rhaub hauv dej da dej ntawm 50 ~ 70 degree, khaws cia sov li 1h, tom qab ntawd sawv ntawm chav sov li 8h, ntws thiab lim. , ntxuav nrog dej rau pH 6 ~ 7, ces ntxuav nrog 50% cawv tov thiab qhuav kom tau baicalin.
Yog koj xav paub ntxiv, thov hu rausales@sxytbio.com,Nyem qhov no los tiv tauj peb hauv online
