Hais Txog Cov Lus Qhia Ntxiv NtawmLinolenic acid?

Linolenic acid roj muaj nyob rau hauv cov nroj tsuag ntsuab tsaus nyob rau hauv daim ntawv ntawm glycerides thiab yog lub ntsiab ntawm tib neeg cov ntaub so ntswg hlwb.
Muaj ob isomers: alpha-linolenic acid thiab gamma-linolenic acid. Tus qub lub npe scientific yog "cis-octadecatriene-9,12,15-acid". belongs rau omega -3 series ntawm unsaturated fatty acids. Nws yog xim tsis muaj xim rau lub teeb daj. Nws yog yooj yim oxidized nyob rau hauv cov huab cua, insoluble nyob rau hauv dej, thiab soluble nyob rau hauv organic solvents xws li ethanol thiab ether. Nws muaj nyob rau hauv ntau cov roj qhuav hauv daim ntawv ntawm glycerides, tshwj xeeb tshaj yog cov roj taum pauv thiab perilla roj. Nws yog ib qho tseem ceeb fatty acids nyob rau hauv tib neeg lub cev thiab muaj ntau yam physiological functions ntawm tib neeg lub cev, xws li txo cov ntshav lipids thiab tiv thaiv thrombosis. Ntxiv nrog rau kev siv los ua cov khoom kho mob, nws kuj yog ib qho tseem ceeb ntawm cov khoom siv tshuaj. Lub tom kawg lub npe scientific yog "cis-octadecatriene-6,9,{10}}acid". belongs rau omega -6 series ntawm fatty acids. Piv txwv li, blackcurrant noob roj, yav tsaus ntuj primrose roj, borage roj, thiab lwm yam. muaj cov ntsiab lus siab dua. Nws muaj ntau yam kev saib xyuas kev noj qab haus huv rau tib neeg lub cev, xws li tswj cov ntshav lipids, tiv thaiv thrombosis, prostaglandin precursors, thiab lwm yam tuaj yeem siv los ua cov khoom kho mob thiab tshuaj. Nws tuaj yeem hloov pauv los ntawm linoleic acid hauv tib neeg lub cev.

Daim ntawv teev cov khoom

CAS	463-40-1
Cov mis mos molecular	C18H30O2
Molecular hnyav	278.43
EINECS	207-334-8
Melting point	-11 degree (lit.)
Boiling point	230-232 degree 1mmHg (lit.)
Qhov ntom	0.914g/mLat25 degree (lit.)
FEMA	3380
Refractive Index	n20/D1.480 (lit.)
Flash point	>230 degree F
Solubility	Chloroform, EthylAcetate (me ntsis), Methanol (me ntsis)
Acidity coefficient (pKa)	4.78 ± 0.10 (Tshaj tawm)

Cov txiaj ntsig yog dab tsi?

1. Tswj cov ntshav lipids
Hauv cov txheej txheem ntawm -linolenic acid txo qis cov roj (cholesterol) hauv cov ntshav, ntxiv rau kev nce cov roj cholesterol, inhibiting endogenous cholesterol synthesis kuj tseem ceeb. HMG-CoA yog lub ntsiab tus nqi-txheej enzyme rau cov cholesterol synthesis, thiab -linolenic acid inhibits nws cov dej num thiab txo cov cholesterol synthesis. Tield et al. pom tias kev noj cov tshuaj -linolenic acid tuaj yeem txo cov haujlwm ntawm luav daim siab HMG-CoA reductase thiab ua kom cov haujlwm ntawm ACAT. -Linolenic acid inhibits rog synthesis enzymes thiab txhim khu -oxidation nyob rau hauv mitochondria, txo triglyceride synthesis thiab nce noj. -Linolenic acid tuaj yeem txo cov ntshav lipids hauv cov luav yam tsis muaj cov lipids nyob rau hauv daim siab. Txawm hais tias linoleic acid thiab -linolenic acid, uas yog omega -6 PUFAs, kuj muaj cov txiaj ntsig ntawm kev txo cov ntshav lipids, lawv feem ntau txhawb kev hloov cov lipids ntawm cov ntshav mus rau cov ntshav. Lub siab metastasis txo cov ntshav lipids, ua rau lub siab rog.

2. Tiv thaiv infarction
Los ntawm qhov kev xav ntawm lub tshuab ntawm qhov tshwm sim, muaj ob lub ntsiab ntawm thrombus, ib qho yog lipid embolus, thiab lwm yam yog ntshav coagulation. Feem ntau cov tshuaj antithrombotic tsuas yog ua rau ntawm ib qho ntawm cov yam ntxwv, thaum cov nyhuv antithrombotic ntawm -linolenic acid yog ua tiav thiab dav.
-Linolenic acid cov ntshav lipid tswj kev ua haujlwm tuaj yeem txo cov roj cholesterol, triglycerides, LDL, VLDL, nce HDL, thiab tawm dag zog los tiv thaiv thrombotic. Tom qab noj 1.2g / d ntawm -linolenic acid rau 120 hnub, qhov ceev ntawm cov roj cholesterol nyob rau hauv lub tshuab ntsuas yuav txo qis, thiab cov lipid plaques loj tuaj yeem ploj mus.

3. Txo cov viscosity thiab nce cov pa oxygen

Tsis muaj cov tshuaj tsom rau ntshav viscosity. Hauv qhov no, alpha-linolenic acid muaj nws lub luag haujlwm tshwj xeeb. Alpha-linolenic acid tuaj yeem tswj cov metabolism hauv qab zib, rog thiab protein, txo cov qib ntawm cov protein ntau hauv cov ntshav, thiab ua kom cov ntshav fluidity. Cov nyhuv tuaj yeem pom tom qab ntxiv alpha-linolenic acid rau li 90 hnub. Qhov kev faib ua feem ntawm -linolenic acid nyob rau hauv lub cell membrane phospholipids nce, fluidity ntawm daim nyias nyias nce, thiab tus nqi ntawm cov cell membrane nto nce. Qhov adhesion ntawm cov hlwb tuaj yeem txhim kho tau zoo. Lub adhesion ntawm cov hlwb feem ntau pom tseeb tom qab 30 hnub ntawm kev ntxiv -linolenic acid. kev tawg. Cov neeg mob hyperviscosity tau ntxiv nrog -linolenic acid ntawm 1.5g / d rau 90 hnub, thiab tag nrho cov ntsuas tau rov qab los. Cov tsos mob xws li palpitations, hauv siab nruj, kiv taub hau, insomnia, tsis nco qab, thiab loog loog tau kho kom zoo, nrog rau qhov zoo ntawm 90%. saum toj no.

4. Rau ntshav qab zib
-Linolenic acid tuaj yeem txhawb kev tso tawm ntawm cov tshuaj insulin los ntawm insulin -cells thiab tswj kev ruaj ntseg ntawm insulin hauv cov ntshav. Nws tuaj yeem txo qhov tsis kam ntawm cov hom phiaj rau cov tshuaj insulin, ua kom cov tshuaj insulin rhiab heev ntawm cov cell membrane, thiab txo cov tshuaj insulin antagonism.
Alpha-linolenic acid tuaj yeem tswj cov lipid metabolism hauv tib neeg lub cev, tiv thaiv cov teeb meem, thiab txo cov kua qaub thiab ketosis lom. Nyob rau tib lub sijhawm, -linolenic acid tiv thaiv thiab txhim kho cov teebmeem ntawm ntau yam kabmob thiab lub paj hlwb ntawm tib neeg lub cev muaj txiaj ntsig zoo rau cov ntshav qab zib.

5. Txo cov ntshav siab
Alpha-linolenic acid thiab nws cov metabolites EPA thiab DHA tuaj yeem txo cov ntshav siab ntawm cov neeg mob ntshav siab. Kev noj 1.2 grams tauj ib hnub tuaj yeem txo cov ntshav siab, diastolic ntshav siab thiab txhais tau tias cov ntshav siab los ntawm 10mmHg, thaum cov ntshav siab yuav luag tsis cuam tshuam. Lub tshuab uas ω-3PUFA txo qis ntshav siab ntseeg tau tias yog cov lus teb ntawm cov tshuaj endogenous vasoactive rau cov hlab ntsha, xws li vasodilation nyhuv ntawm prostacycline PGI3, uas txhawb nqa cov hlwb endothelial tso tawm NO, thiab tib lub sijhawm , -linolenic acid tuaj yeem ua rau cov ntshav plasma roj (cholesterol, triglyceride) cov ntsiab lus txo qis.

6. Tiv thaiv kev tsis haum tshuaj

Kev hloov pauv ntawm qhov sib txawv ntawm ntau hom fatty acids tseem ceeb hauv cov zaub mov tuaj yeem ua rau muaj kev tsis haum xeeb hauv lub cev. Vim tias 4-series leukotrienes LT4 (LTB4, LTC4, LTD4, LTE4) ua los ntawm ω-6 PUFA arachidonic acid, thiab 5-series leukotrienes LT5 (LTB5, LTC5, LTD5, LTE4) ua los ntawm -linolenic acid LTE5). LTB4 tuaj yeem nyiam cov neutrophils, eosinophils, thiab monocytes thiab nce permeability ntawm cov hlab ntsha phab ntsa. Txawm li cas los xij, kev ua haujlwm ntawm lub cev ntawm LT5 hauv qhov no tsuas yog ob peb feem kaum rau ob peb puas ntawm qhov ntawm LT4. Cov nas tsuag tau muab cov khoom noj siab hauv alpha-linolenic acid thiab siab linoleic acid (safflower roj) rau ob tiam neeg. Glycogen tau txhaj tshuaj intraperitoneally kom sib sau cov neutrophils, txhawb kom tso cov tshuaj LT, thiab tom qab ntawd suav nrog. Tsis muaj qhov sib txawv loj ntawm tag nrho cov nyiaj ntawm LT tso tawm, tab sis muaj qhov sib txawv loj hauv qhov sib piv ntawm hom B4 nquag nquag thiab tsis muaj zog B5 hom.

7. Anti-inflammatory nyhuv
Nrog rau kev siv tshuaj tua kab mob thiab lwm yam tshuaj tua kab mob, qhov cuam tshuam ntawm cov kab mob pathogenic rau tib neeg kev noj qab haus huv tau qis zuj zus mus ib hnub, thaum qee qhov tsis muaj kab mob thiab tsis ua rau mob hnyav ua rau muaj kev hem thawj rau tib neeg kev noj qab haus huv thiab cuam tshuam rau tib neeg lub neej zoo, xws li Rau rheumatism, rheumatoid mob caj dab, mob rhinitis, mob prostatitis, thiab lwm yam., antipyretic analgesics, non-steroidal anti-inflammatory tshuaj thiab hormonal anti-inflammatory tshuaj tsuas yog ua si lub luag hauj lwm ntawm cov tsos mob ntawm tus kab mob no. Uas yog hais, nws txo cov synthesis ntawm ntau yam inflammatory mediators, tab sis nyob rau tib lub sij hawm ua rau muaj kev phiv loj heev rau lub cev. Alpha-linolenic acid muaj cov nyhuv inhibitory ntawm ntau yam inflammatory mediators thiab cytokines tsis ua rau muaj kev phiv tshuaj, coj cov tswv yim tshiab rau kev kho mob ntawm hom kab mob no.

8. Tiv thaiv qhov muag
Raws li tau hais ua ntej, ntu sab nraud ntawm cov hlwb pom hauv lub retina muaj qhov tshwj xeeb ntawm DHA. Yog tias DHA tsis txaus, qhov muag yuav txo qis thiab lub sijhawm rov qab los ntawm lub zog retinal reflex yuav ntev. Vim tias sai li sai tau thaum lub retina ntsib lub teeb, nws nkag mus rau cov tshuaj tiv thaiv tshuaj, ua rau muaj kev hloov pauv hauv hluav taws xob, uas tau kis mus rau lub hlwb los ntawm cov hlab ntsha. Cov nas tau noj nrog Ω-6 series safflower roj thiab -linolenic acid rau ob tiam neeg, thiab tom qab ntawd muab lub teeb sib txawv los tsim cov kev hloov pauv los sib piv qhov loj (amplitude) ntawm yoj thiab nthwv dej hauv lub cell membrane muaj peev xwm daim duab. los txiav txim qhov retinal reflectance zog. Cov txiaj ntsig tau pom tias qhov amplitude ntawm lub amplitude sib raug rau cov ntsiab lus ntawm -linolenic acid, uas yog, nws nce nyob rau hauv qhov kev txiav txim ntawm safflower roj, tswj pawg, thiab -linolenic acid. Kev sim nrog cov liab kuj tau ua pov thawj tias -linolenic acid deficiency txo qhov pom kev.

9. Txhim khu kev txawj ntse
Docosahexaenoic acid (DHA) muab tau los ntawm -linolenic acid yog tam sim no nyob rau hauv loj npaum li cas nyob rau hauv lub cranial qab haus huv thiab retina, thiab tseem ceeb heev rau lub hlwb kev loj hlob ntawm fetus mus rau lactation. Thaum lub sij hawm weaning, feem ntau ntawm lub paj hlwb kev faib tawm tau xaus, thiab cov paj hlwb yuav tsis nce ntau yav tom ntej. Yog li, -linolenic acid supplementation los ntawm cev xeeb tub mus rau lactation yog qhov tsim nyog heev.

Tsis tas li ntawd, alpha-linolenic acid kuj muaj kev tiv thaiv kev laus, tiv thaiv kev nyuaj siab, thiab tiv thaiv cov kab mob Alzheimer. Nws yog ib qho tseem ceeb rau kev tswj hwm tib neeg txoj kev loj hlob thiab kev loj hlob thiab tswj cov tawv nqaij ib txwm muaj.

Dab tsi yog Daim Ntawv Qhia Cov Lus Qhia?

alpha-Linolenic acid roj
-Linolenic acid (ALA) yog octadecatrienoic acid, ib qho tseem ceeb unsaturated fatty acid rau tib neeg lub cev. Cov khoom noj uas nplua nuj nyob rau hauv -linolenic acid muaj xws li safflower roj, sunflower roj, soybean roj, pob kws roj, sesame roj, txiv laum huab xeeb, roj camellia, thiab rapeseed roj. Qhov no alpha-linolenic acid tuaj yeem metabolized rau hauv eicosapentaenoic acid (EPA) thiab docosahexaenoic acid (DHA) hauv tib neeg lub cev, yog li nws cov haujlwm hauv lub cev zoo ib yam li EPA thiab DHA.
(1) Khoom noj khoom haus fortifiers
Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb (WHO) thiab Lub Koom Haum Saib Xyuas Khoom Noj thiab Kev Ua Liaj Ua Teb ntawm United Nations (FAO) solemnly pom zoo rau lub ntiaj teb cov roj fatty acids: monounsaturated fatty acids: polyunsaturated fatty acids=1: 1: 1. Polyunsaturated fatty acids muaj xws li linoleic acid thiab linolenic acid.
(2) Ua cov khoom noj ntxiv
-Linolenic acid feem ntau pom nyob rau hauv daim nyias nyias lipids ntawm cov nroj tsuag chloroplast grana, uas yog, nyob rau hauv lub photoreceptors ntawm cov nroj tsuag. Perilla noob yog nplua nuj nyob rau hauv alpha-linolenic acid thiab yog ib tug zoo zoo tej yam ntuj tso nroj tsuag qhov chaw ntawm alpha-linolenic acid. Tsis tas li ntawd, perilla noob muaj roj cov ntsiab lus, thiab cov ntsiab lus tseem ceeb yog -linolenic acid, nrog cov ntsiab lus siab txog 50% mus rau 60%. Siv perilla noob extract raws li pub additive tuaj yeem muab polyunsaturated fatty acids (PUFA) xav tau rau kev loj hlob thiab kev loj hlob ntawm cov tsiaj nyeg thiab nqaij qaib. Cov khoom lag luam nrog -linolenic acid ua cov khoom tseem ceeb muaj cov haujlwm hauv qab no: ua kom cov enzymes cuam tshuam hauv cov tsiaj nyeg, nqaij qaib, cov khoom siv hauv dej thiab cov tsiaj tshwj xeeb, txhawb nqa lawv cov metabolism thiab assimilation, accelerating kev loj hlob, shortening lub voj voog pub mis, thiab txo tus nqi pub mis. Vim hais tias polyunsaturated fatty acids tuaj yeem cuam tshuam rau lub cev cov roj metabolism, nws muaj feem xyuam rau nws lub peev xwm los tswj cov kev qhia ntawm cov roj metabolism hauv cov enzymes thiab cov noob protein. Tsis tas li ntawd, cov kev tshawb fawb tau pom tias ntxiv polyunsaturated fatty acids rau kev noj haus kuj tuaj yeem cuam tshuam cov roj deposition hauv cov tsiaj.
-linolenic acid
(1) Siv nyob rau hauv cov tshuaj pleev ib ce
-Linolenic acid tuaj yeem cuam tshuam tyrosinase, tiv thaiv melanin ntau lawm, tiv thaiv pigmentation, txhawb cov ntshav ncig thiab cell metabolism, thiab muaj txiaj ntsig zoo rau kev kho mob thiab kev noj haus ntawm daim tawv nqaij thiab plaub hau, yog li nws tau siv dav hauv cov tshuaj pleev ib ce. Raws li ib tug natural roj raw khoom rau cov tshuaj pleev ib ce, cov roj nplua nuj nyob rau hauv -linolenic acid yuav siv tau raws li cov roj pleev xim, moisturizing lotions, rejuvenating cream thiab lwm yam khoom siv ntawm daim tawv nqaij, nrog rau cov roj rau ntau yam khoom tu plaub hau, raws li zoo raws li cov tawv nqaij ntxuav hniav dawb, moisturizing, thiab anti-aging agents. Element. Ntxiv gamma-linolenic acid thiab niacin derivatives rau tshuaj zawv plaub hau tuaj yeem txhim kho kev nkag mus.
(2) Ua cov khoom noj ntxiv
-Linolenic acid tuaj yeem ua rau lub cev superoxide dismutase thiab catalase kev ua ub no, thiab txo qis kev tsim cov peroxidized lipids hauv plasma. Ntxiv -linolenic acid rau pub tuaj yeem tiv thaiv tsiaj kab mob, txo kev tuag, thiab pab kom ruaj khov (nce) cov ntsiab lus -linolenic acid hauv cov khoom noj tsiaj (xws li qe thiab mis nyuj).

Tuam txhab Taw Qhia Thiab Daim Ntawv Pov Thawj Tau Txais

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) tau tsim nyob rau xyoo 2014, feem ntau muab cov roj Linolenic acid thiab lwm yam. Peb muaj peb tus kheej cov chaw tsim khoom, R&D thiab pab pawg soj ntsuam zoo, thiab muaj cov xwm txheej rau kev txhim kho, ntau lawm, thiab kev ruaj ntseg zoo. Tam sim no, peb tau txais ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, thiab lwm yam ntawv pov thawj. Yog li ntawd, qhov zoo ntawm peb cov khoom yog guaranteed, thiab nws yog peb lub hom phiaj thawj coj cov khoom zoo rau cov neeg muas zaub.

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