Buddleoside

Shaanxi Yuantai Biological Technology Co., Ltd. yog ib qho ntawm feem txhim khu kev qha manufacturers thiab lwm tus neeg ntawm buddleoside nyob rau hauv Suav teb. Nrog kev paub ntau, peb sov siab txais tos koj rau cov lag luam wholesale buddleoside muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.

Buddleoside (linarin)Nws yog ib qho khoom siv tshuaj lom neeg uas pom dav hauv cov nroj tsuag tshuaj xws li qus chrysanthemum, buddleja, mint thiab buddleja. Nws cov monomer yog cov hmoov dawb crystalline, uas yooj yim soluble hauv methanol. Linarin feem ntau yog muab los ntawm cov tsiaj qus chrysanthemum, uas cov ntsiab lus ntawm linarin nyob rau hauv qus chrysanthemum nyob rau hauv lub Dabie Roob cheeb tsam nyob rau hauv lub hlws ris ntawm Anhui, Henan thiab Hubei xeev kuj siab. Nrog rau hauv - kev tshawb fawb tob ntawm linarin, nws tau pom tias nws muaj ntau yam tshuaj ua haujlwm xws li tshuaj tiv thaiv - mob, antioxidant thiab tiv thaiv - qog.

Raws li cov khoom xyaw tseem ceeb ntawm cov qus chrysanthemum, linarin muaj ntau yam tshuaj muaj txiaj ntsig, suav nrog kev tiv thaiv neuroprotection thiab kev tiv thaiv kab mob plawv, thiab tau pom cov txiaj ntsig zoo hauv kev tiv thaiv - mob, antioxidant thiab tiv thaiv - qog nqaij hlav. Tsis tas li ntawd, linarin tuaj yeem tswj cov pob txha metabolism thiab txhim kho daim siab thiab lub raum puas. Cov kev tshawb fawb no muaj txiaj ntsig tseem ceeb rau kev nthuav dav nws daim ntawv thov kho mob.

YTBIO cov khoom siv10% thiab 98%Buddleoside specifications, tsim nyog rau kev txhim kho cov khoom noj khoom haus, cov khoom noj khoom haus, thiab cov khoom tu tawv nqaij, nrog rau kev xa tawm - qib kev noj qab haus huv, cov khoom siv tshuaj, thiab siab - cov qauv tsim nyog.Tag nrho peb cov txheej txheem tsim khoom nruj me ntsis ua raws li cov ntawv pov thawj thoob ntiaj teb xws li cGMP, FSSC220SH, AL, FSSC2200, AL, cGMP, FSSC2200, H. ISO 22000. Peb txhawb MOQ hloov tau yooj yim thiab me me - qauv kuaj. Thov koj xav tiv tauj peb rau cov lus tshaj tawm tshiab.

Antihypertensive nyhuv
Chrysanthemum yog siv rau ntau yam kab mob xws li kub siab. Nws tag nrho cov flavonoids (luteolin thiab oleanolic acid) ntseeg tau los tswj cov hlab ntsha thiab txo cov ntshav siab. Cov kev tshawb fawb tau pom tias kev sib xyaw ntawm luteolin thiab oleanolic acid tuaj yeem cuam tshuam cov qib ntawm angiotensin (Ang), aldosterone thiab endothelin, thiab ua kom cov ntshav tsis muaj concentration. Tom qab kev tswj hwm ntawm ob qho tib si, systolic ntshav siab (SBP) thiab diastolic ntshav siab (DBP) poob los ntawm 9.37% thiab 12.67%, feem. Hauv kev sim hauv vitro vascular nplhaib nro, nws tau pom tias lub nplhaib vascular so ntawm oleanolic acid ua ke nrog luteolin (1:4) yog siab dua li ntawm ib leeg, thiab kev sib xyaw ua ke ntawm ob tuaj yeem ua rau muaj kev nthuav qhia ntawm p-Akt thiab p-eNOS proteins, uas tej zaum yuav yog los ntawm kev ua kom lub PI3Kh/Akt ntawm kev ua, txoj hauv kev, nce cov synthesis thiab tso tawm NO, thiab ua tiav cov txiaj ntsig ntawm vasodilation. Kev tswj hwm intragastric ntawm 75 mg / kg linaloside tuaj yeem txo lub sijhawm kiv taub hau ntawm cov nas uas muaj ntshav siab ntau thiab txo SBP, DBP thiab txhais tau tias cov ntshav siab. Nws kuj tseem tuaj yeem cuam tshuam qhov kev loj hlob tsis zoo thiab kev tsiv teb tsaws ntawm thawj vascular du leeg hlwb VSMCs, thiab txo qis cov protein qhia qib ntawm AngII, angiotensin type 1 receptor (AT1), MMP-2, MMP-9 thiab p-Src, qhia tias linaloside tuaj yeem cuam tshuam qhov ua rau ntawm aortic pathogens, tom qab ntawd cov teeb liab cuam tshuam rau AT1, thiab kev cuam tshuam ntawm cov kab mob hauv lub plawv. thiab tsiv teb tsaws ntawm vascular du leeg hlwb, yog li exerting anti-hypertensive vascular remodeling nyhuv.

Neuroprotective nyhuv
Acetylcholinesterase (AchE) yog lub hom phiaj tseem ceeb rau kev kho mob Alzheimer's disease (AD). Cov kev tshawb fawb tau pom tias linaloside muaj kev xaivinhibitory nyhuv ntawm AchE nyob rau hauv ib koob tshuaj -nyob ntawm seb. Tom qab KM nas tau txhaj tshuaj intraperitoneally nrog cov koob tshuaj sib txawv ntawm madagascar glycosides (35, 70 thiab 140 mg / kg), nws tau pom tias AchE kev ua haujlwm hauv cerebral cortex thiab hippocampus ntawm cov nas tau txo qis. Cov nyhuv inhibitory ntawm siab - koob tshuaj madagascar glycosides yog sib npaug ntawm kev kho huperzine A (0.5 mg / kg). Molecular docking cov kev tshawb fawb pom tau tias 4'-methoxy thiab 7-O-cov suab thaj ntawm madagascar glycosides ua lub luag haujlwm tseem ceeb hauv ligand-receptor khi thiab yog lub luag haujlwm tseem ceeb rau inhibiting AchE kev ua haujlwm. Lwm txoj kev tshawb nrhiav pom tias dhau los ntawm kev sim ua qauv molecular docking, ib qho txhuas chloride-induced zebrafish Alzheimer tus kab mob qauv tau tsim. Donepezil (DPZ) tau siv los ua cov tshuaj tswj tau zoo los sib piv cov teebmeem ntawm montanol ntawm AD zebrafish txav tsis meej thiab AchE inhibition. Cov txiaj ntsig tau pom tias qhov kev txav mus los tsis zoo rov qab thiab AchE inhibition tus nqi hauv 16.7 thiab 50ug / mL montanol (3d) pawg yog 88.0% thiab 74.5%, feem, thiab pawg DPZ yog 79.3% thiab 43.6%. Yog li, montanol tuaj yeem tsis tsuas yog txhim kho kev rov qab los ntawm kev txav mus los, tab sis kuj tseem cuam tshuam AchE kev ua haujlwm. Cov txiaj ntsig kev tshawb fawb no muab qee qhov kev sim hauv paus rau kev siv tshuaj montanol hauv kev kho mob Alzheimer's.

Lwm yam teebmeem
Ntxiv rau cov teebmeem saum toj no, 144ug/mL montanol kuj muaj cov tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, thiab tiv thaiv- cov teebmeem kev laus. Qhov tsawg kawg nkaus inhibitory concentration ntawm tag nrho cov flavonoids los ntawm qus chrysanthemum tiv thaiv Candida portugalensis yog 61.6 ug / mL, thaum qhov tsawg kawg nkaus inhibitory concentration ntawm lignoside yog 18.0 ug / mL, nrog zoo nyob rau hauv vitro antibacterial kev ua. Lignoside kuj tseem muaj cov tshuaj tua kab mob thiab tshuaj tua kab mob. Lignoside tuaj yeem txo qis kev qhia qib ntawm senescence-txog cov proteins p16, p21, thiab p53 hauv cov hlwb senescent, thiab cov xov tooj ntawm cov hlwb zoo rau cov protein ntau ntawm cov protein -H2AX protein cuam tshuam nrog DNA puas tau txo qis, qhia tias lignoside tuaj yeem ua lub luag haujlwm tiv thaiv - hom laus los ntawm kev tshem tawm cov pob txha phenescent. mesenchymal qia hlwb, thiab nws yog koob tshuaj - nyob ntawm.

Pharmaceuticals:Siv los ua cov khoom siv raw hauv kev tiv thaiv- tshuaj tsis haum thiab ua pa thiab tshuaj noj.

Tshuaj pleev ib ce:Siv nws cov tshuaj ntxuav hniav dawb thiab soothing, nws ntxiv rau ntau yam kev tu tus kheej thiab cov khoom tu tawv nqaij.

Yav tom ntej Prospects

Buddleoside yog ntau- cov hom phiaj cov khoom xyaw uas muaj peev xwm siv tau rau hauv cov kab mob hauv lub paj hlwb thiab cov hlab plawv, nrog rau siab - cov tshuaj pleev ib ce kawg.

Yog tias koj txaus siab rau YTBIO's Buddleoside, thov koj xav tiv tauj peb ntawm kev sib tham hauv online lossis email. Peb yuav muab koj nrog kev txhawb nqa kev tshaj lij thiab kev daws teeb meem.

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Cim npe nrov: Tuam Tshoj buddleoside manufacturers, lwm tus neeg, Hoobkas